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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LAT2 / NTAL Antibody (aa91‑243, clone NAP‑07) LS‑C46032 Best Seller
Antibody
NTAL antibody LS-C46032 is an unconjugated mouse monoclonal antibody to NTAL (LAT2) from human and mouse. Validated for Flow, ICC, Inhb, IP and WB.
Catalog
Size
Price
LS-C46032-100
100 µg (1 mg/ml)
Unavailable

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Product Description

NTAL antibody LS-C46032 is an unconjugated mouse monoclonal antibody to NTAL (LAT2) from human and mouse. Validated for Flow, ICC, Inhb, IP and WB.
About LAT2 / NTAL
Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. Q9GZY6 NM_022040 NP_115853.2

LAT2 Antibody, HSPC046 Antibody, Non-T-cell activation linker Antibody, NTAL Antibody, LAB Antibody, WBSCR15 Antibody, WBS15 Antibody, WBSCR5 Antibody, WSCR5 Antibody


Specifications

Target
Human LAT2 / NTAL
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [NAP-07]
Conjugations
Unconjugated. Also available conjugated with PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot (2 µg/ml)
  • Immunoprecipitation (2 µg/ml)
  • Flow Cytometry
  • Inhibition
  • (applications tested for the base form of this product only)
Immunogen
LAT2 / NTAL antibody was raised against recombinant cytoplasmic domain (aa 91-243) of human NTAL.
Epitope
aa91-243
Specificity
Reacts with Non-T cell activation linker (NTAL), also known as LAB (linker of activated B cells), a 25 - 30 kD transmembrane adaptor protein present in membrane microdomains (rafts) of B lymphocytes, NK cells and myeloid cells.
Usage
Flow Cytometry: Positive tissue -. RAJI human lymphoma cell line. RAMOS human lymphoma cell line. Western Blotting: Recommended dilution - 2 ug/ml, incubation 60 min. Positive control -. RAMOS human lymphoma cell line. Negative control -. HeLa human cervi
Presentation
PBS, 15 mM sodium azide, approx., pH 7.4.
Storage
Store at 2-8°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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