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Anti-LAMTOR1 Antibody (aa50-250) LS-C143599
Most Popular LAMTOR1 Antibodies
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Details
| Human LAMTOR1 | |
| Rabbit | |
| Human, Mouse (tested or 100% immunogen sequence identity) | |
| Bovine (at least 90% immunogen sequence identity) | |
| Polyclonal | |
| Unconjugated | |
| Immunoaffinity purified | |
| Unmodified |
Applications
- IHC - Paraffin (1:25 - 1:100)
- ICC (1:25 - 1:100)
- Immunofluorescence (1:25 - 1:100)
- Western blot (1:1000)
Specificity and Use
| LAMTOR1 antibody was raised against a genomic peptide made to an C-terminal region of the human c11orf59 protein (within residues 50-250). [Swiss-Prot Q6IAA8]. Percent identity by BLAST analysis: Bovine (98%). | |
| aa50-250 |
Packaging
| PBS, 0.1% BSA, 50% glycerol, 0.05% sodium azide | |
| Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. | |
| For research use only. |
About LAMTOR1
Q6IAA8
NM_017907
NP_060377.1
LAMTOR1 Antibody, C11orf59 Antibody, Ragulator1 Antibody, p27RF-Rho Antibody, PDRO Antibody, RhoA activator C11orf59 Antibody, Lipid raft adaptor protein p18 Antibody, p18 Antibody, Ragulator complex protein PDRO Antibody
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated.
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Requested From:
Date Requested: 6/24/2017
Date Requested: 6/24/2017
