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Lamin C

In animal cells, there are A- and B-type lamins, which differ in their length and isoelectric point (pI). Human cells have three differentially regulated genes. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively. A-type lamins are expressed only following gastrulation. Lamin A and C are the most common A-type lamins and are splice variants of the LMNA gene found at 1q21.

Lamin C Target Details

Target Name: Lamin C

Publications (2)

1
Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. Jung HJ, Coffinier C, Choe Y, Beigneux AP, Davies BS, Yang SH, Barnes RH, Hong J, Sun T, Pleasure SJ, Young SG, Fong LG. Proceedings of the National Academy of Sciences of the United States of America. 2012 109:E423-31. (IHC-Fr; Mouse, Human) [Full Text Article] [PubMed:22308344] [PMC:PMC3289373] Related Antibodies: LS-B2972.
2
An absence of nuclear lamins in keratinocytes leads to ichthyosis, defective epidermal barrier function, and intrusion of nuclear membranes and endoplasmic reticulum into the nuclear chromatin. Jung HJ, Tatar A, Tu Y, Nobumori C, Yang SH, Goulbourne CN, Herrmann H, Fong LG, Young SG. Molecular and cellular biology. 2015 Dec;34:4534-44. [Full Text Article] [PubMed:25312645] [PMC:PMC4248738] Related Antibodies: LS-B2972.

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Lamin C Antibody - Anti-Lamin C antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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Lamin C Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.05 ml/$485
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).