Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human LAMC2 / Laminin Gamma 2
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Rabbit Polyclonal to Human LAMC2 / Laminin Gamma 2
IHC, IHC - Paraffin, Western blot
Human LAMC2 / Laminin Gamma 2
Human (tested or 100% immunogen sequence identity)
Dog, Horse (at least 90% immunogen sequence identity)
IHC - Paraffin (1:100 - 1:1000)
Western blot (1:500 - 1:3000)
Specificity and Use
Recombinant fragment corresponding to a region within amino acids 445 and 657 of Laminin gamma 2 (SwissProt Q13753). Percent identity by BLAST analysis: Human (100%); Dog (92%); Horse (90%); Rat (88%); Mouse (87%); Sheep (84%).
IHC-paraffin: Suggested antigen retrieval using heat mediated 10 mM Citrate buffer (pH 6.0) or Tris-EDTA buffer (pH 8.0).
0.1 M Tris-glycine, pH 7.0, 20% glycerol, 0.01% Thimerosal
Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis.