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LAMA5 / Laminin Alpha 5

laminin, alpha 5

Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined.

Gene Name: laminin, alpha 5
Family/Subfamily: Laminin , not assigned-Laminin
Synonyms: LAMA5, KIAA0533, KIAA1907, Laminin alpha-5 chain, Laminin-10 subunit alpha, Laminin subunit alpha-5, Laminin, alpha 5, Laminin-11 subunit alpha, Laminin-15 subunit alpha
Target Sequences: NM_005560 NP_005551.3 O15230

Publications (2)

1
Laminin 511 is a target antigen in autoimmune pancreatitis. Masahiro Shiokawa, Yuzo Kodama, Kiyotoshi Sekiguchi, Takeshi Kuwada, Teruko Tomono, Katsutoshi Kuriyama, Hajime Yamazaki, Toshihiro Morita, Saiko Marui, Yuko Sogabe, Nobuyuki Kakiuchi, Tomoaki Matsumori, Atsushi Mima, Yoshihiro Nishikawa, Tatsuki Ueda, Motoyuki Tsuda, Yuki Yamauchi, Yojiro Sakuma, Takahisa Maruno, Norimitsu Uza, Tatsuaki Tsuruyama, Tsuneyo Mimori, Hiroshi Seno, Tsutomu Chiba. Science translational medicine. 2018 August;10: [Full Text Article] [PubMed:30089633] Related Antibodies: LS-C144882.
2
Biallelic mutations in LAMA5 disrupts a skeletal noncanonical focal adhesion pathway and produces a distinct bent bone dysplasia. Maya Barad, Fabiana Csukasi, Michaela Bosakova, Jorge H Martin, Wenjuan Zhang, S Paige Taylor, Ralph S Lachman, Jennifer Zieba, Michael Bamshad, Deborah Nickerson, Jessica X Chong, Daniel H Cohn, Pavel Krejci, Deborah Krakow, Ivan Duran. EBioMedicine. 2020 November;62:103075. [Full Text Article] [PubMed:33242826] [PMC:PMC7695969] Related Antibodies: LS-C352437.

☰ Filters
Antibodies (29)
ELISA Kits (6)
Proteins (4)
Primary (29)
Recombinant (4)
Sandwich (6)
LAMA5 / Laminin Alpha 5 (39)
Human (23)
Mouse (18)
IHC (5)
IHC-P (4)
WB (20)
ELISA (9)
IF (2)
IP (3)
Peptide-ELISA (3)
rabbit (25)
mouse (3)
goat (1)
Product Group
IHCPlus (2)
IgG (14)
IgG1,k (1)
IgG2a (2)
monoclonal mc (3)
polyclonal pc (26)
2F7 (1)
4C7 (2D8/33) (1)
96-Well Strip Plate (6)
APC (1)
APC Conjugated (2)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (14)
aa3517-3718 (8)
2350-2430 aa, Internal (1)
C-Terminus (1)
Internal (1)
aa1029-1043 (1)
aa2371-2420 (1)
aa2381-2430 (1)
No (37)
Yes (2)
Plasma (6)
Serum (6)
Tissue Homogenates (4)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (1)
Human (3)
Mouse (1)
E. coli (2)
Wheat Germ Extract (2)
Purified (2)
LAMA5 / Laminin Alpha 5 Antibody - Immunohistochemical analysis of Laminin alpha 5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
WB
Unconjugated
100 µl/$440; 200 µl/$468
LAMA5 / Laminin Alpha 5 Antibody - Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using LAMA5 Antibody. The picture on the right is blocked with the synthesized peptide.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal (aa2381-2430) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
LAMA5 / Laminin Alpha 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
LAMA5 / Laminin Alpha 5 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal (aa2371-2420) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
LAMA5 / Laminin Alpha 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
250 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
LAMA5 / Laminin Alpha 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LAMA5 / Laminin Alpha 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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LAMA5 / Laminin Alpha 5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IP
Unconjugated
100 µl/$842
LAMA5 / Laminin Alpha 5 Antibody - Human Skeletal Muscle, Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 5 ug/ml.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal (2350-2430 aa, Internal) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
LAMA5 / Laminin Alpha 5 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
LAMA5 / Laminin Alpha 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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LAMA5 / Laminin Alpha 5 Mouse anti-Human Monoclonal (4C7 (2D8/33)) Antibody
Human
ELISA, IF, IP
Unconjugated
50 µl/$866
LAMA5 / Laminin Alpha 5 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using LAMA5 antibody.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
100 µg/$357
LAMA5 / Laminin Alpha 5 Antibody - Western Blot analysis of LAMA5 expression in transfected 293T cell line by LAMA5 monoclonal antibody (M01), clone 2F7.Lane 1: LAMA5 transfected lysate(74 KDa).Lane 2: Non-transfected lysate.
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LAMA5 / Laminin Alpha 5 Mouse anti-Human Monoclonal (2F7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
LAMA5 / Laminin Alpha 5 Antibody - Western blot analysis of LAMA5 expression in HEK293 cells. The lane on the left is treated with the antigen-specific peptide.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (APC) Antibody
Mouse
WB
APC Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
LAMA5 / Laminin Alpha 5 Antibody - Western blot of recombinant LAMA5 / Laminin Alpha 5.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LAMA5 / Laminin Alpha 5 Rabbit anti-Mouse Polyclonal (aa3517-3718) (APC, Cy7) Antibody
Mouse
WB
APC, Cy7 Conjugated
100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
LAMA5 / Laminin Alpha 5 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue using LAMA5 Antibody at dilution of 1:100
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LAMA5 / Laminin Alpha 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 39 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).