Human LAIR1 / CD305

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

NKTA255

Unconjugated. Also available conjugated with FITC.

Protein G purified

Unmodified

NK cells lines B12.100 and AM.25

Recognizes human leukocyte-associated Ig-like receptor-1 (LAIR-1), a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other hematopoietic cells including B cells, but is not expressed by non-hematopoietic, platelets or erythrocytes. Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules. XXX recommend the use of MCA2242XZ for this purpose.

• Western blot
• Immunoprecipitation
• Flow Cytometry (1:50 - 1:100)

Western Blot: LS-C44465 detects a band of approximately 40 kD. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q6GTX8 NCBI: CR610686 IPI00032544.1