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Anti-LAIR1 / CD305 Antibody (Biotin) LS-C44462

Note: This antibody replaces LS-C57762


Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Alternate Forms of this Antibody

LS-C44465 Unconjugated
LS-C44464 FITC Conjugated
LS-C44466 RPE Conjugated

Most Popular LAIR1 / CD305 Antibodies

Anti-LAIR1 / CD305 Antibody (APC) LS-C37142
Mouse Monoclonal (IgG2b) to Human LAIR1 / CD305
Flow Cytometry
APC Conjugated
Anti-LAIR1 / CD305 Antibody (clone LC12) IHC-plus™ LS-B2919
Mouse Monoclonal [clone LC12] (IgG1,k) to Human LAIR1 / CD305
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Immunohistochemistry Image
Anti-LAIR1 / CD305 Antibody (aa69-81) IHC-plus™ LS-B8316
Goat Polyclonal to Human LAIR1 / CD305
IHC - Paraffin, Western blot, ELISA
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Human LAIR1 / CD305
Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Biotin Conjugated


Human LAIR1 / CD305
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified


  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:1 - 1:5)
  • (applications tested for the base form of this product only)

Specificity and Use

LAIR1 / CD305 antibody was raised against nK cells lines B12.100 and AM.25.
Recognizes human leukocyte-associated Ig-like receptor-1 (LAIR-1), a 40kD cell surface molecule that functions as an inhibitory receptor on natural killer cells, monocytes and T cells. LAIR-1, otherwise known as CD305, is also expressed by other hematopoietic cells including B cells, but is not expressed by non-hematopoietic, platelets or erythrocytes. Clone NKTA255 is reported to inhibit NK cell triggering via CD16 molecules. XXX recommend the use of MCA2242XZ for this purpose.
The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.


PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
For research use only.

About LAIR1 / CD305

Q6GTX8 CR610686 IPI00032544.1

LAIR1 Antibody, CD305 Antibody, CD305 antigen Antibody, HLAIR1 Antibody, LAIR-1 Antibody

Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases.

Requested From: United States
Date Requested: 10/25/2016

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