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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LAIR1 / CD305 Antibody (aa177‑206) LS‑C165668
CD305 antibody LS-C165668 is an unconjugated rabbit polyclonal antibody to human CD305 (LAIR1). Validated for WB.
Catalog
Size
Price
LS-C165668-400
400 µl
Unavailable

Popular LAIR1 / CD305 Products

Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Flow Cytometry
Antibody
Species: Human
Applications: Western blot, Immunoprecipitation, Flow Cytometry
Staining of C57Bl/6 splenocytes with 0.125 ug of Armenian Hamster IgG isotype control (purple line) or 0.125 ug of anti-mouse LAIR-1 (113) (blue line) followed by Phycoerythrin (PE) anti-Armenian Hamster IgG. Total viable F4/80 positive cells were used for analysis.
Species: Mouse
Applications: Western blot, Immunoprecipitation, Flow Cytometry
Anti-CD305 / LAIR-1 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8316 dilution 3.75 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay

Product Description

CD305 antibody LS-C165668 is an unconjugated rabbit polyclonal antibody to human CD305 (LAIR1). Validated for WB.
About LAIR1 / CD305
Functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells. Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11. It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation. May also play its inhibitory role independently of SH2-containing phosphatases. Q6GTX8 CR610686 IPI00032544.1

LAIR1 Antibody, CD305 Antibody, CD305 antigen Antibody, HLAIR1 Antibody, LAIR-1 Antibody


Specifications

Target
Human LAIR1 / CD305
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
Blocking Peptide
LS-E2705 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C165668. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa177-206
Specificity
This LAIR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-206 amino acids from the Central region of human LAIR1.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).
LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).

Western blot

LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).
LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).

Western blot

LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).
LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).

Western blot

LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).
LAIR1 Antibody western blot of K562 cell line lysates (35 ug/lane). The LAIR1 antibody detected the LAIR1 protein (arrow).


Requested From: 
Date Requested: 6/21/2018

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