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Anti-LAG3 Antibody (clone C9B7W, RPE) LS-C44775

Note: This antibody replaces LS-C57926, LS-C37141
Catalog Size Price
LS-C44775-100 100 tst Unavailable

Related Products

69 LAG3 Antibodies

Most Popular LAG3 Antibodies

Anti-LAG3 Antibody (clone 11E3) LS-C18690
Mouse Monoclonal [clone 11E3] (IgG1) to Human LAG3
Human, Monkey
IHC - Frozen, ICC, Western blot, Immunoprecipitation, ELISA
Unconjugated
Anti-LAG3 Antibody (clone 17B4) LS-C18692
Mouse Monoclonal [clone 17B4] (IgG1) to Human LAG3
Human
IHC - Frozen, ICC, Western blot, Immunoprecipitation
Unconjugated
Anti-LAG3 Antibody (aa70-99, clone 17B4, FITC) IHC-plus™ LS-B2237
Mouse Monoclonal [clone 17B4] (IgG1) to Human LAG3
Human
IHC - Paraffin, Flow Cytometry
FITC Conjugated
Immunohistochemistry Image
Anti-LAG3 Antibody (Extracellular Domain, PerCP) LS-C130398
Goat Polyclonal (IgG) to Human LAG3
Human
Flow Cytometry
PerCP Conjugated
Anti-LAG3 Antibody (clone 17B4, FITC) LS-C344745
Mouse Monoclonal [clone 17B4] (IgG1) to Human LAG3
Human
IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
FITC Conjugated

100% Guaranteed
Rat Monoclonal [clone C9B7W] (IgG1) to Mouse LAG3
Mouse
Flow Cytometry (applications tested for the base form of this product only)
RPE Conjugated

Details

Mouse LAG3
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [C9B7W]
R. Phycoerythrin. Also available Unconjugated.
Protein G purified
Unmodified

Applications

  • Flow Cytometry (1:1 - 1:5)
  • (applications tested for the base form of this product only)

Specificity and Use

LAG3 antibody was raised against murine CD223 Ig fusion protein.
Recognizes murine lymphocyte activation gene-3 (LAG-3), a 70kD activation-induced cell surface molecule that is also referred to as CD223. Murine CD223 is expressed on activated CD4 positive and CD8 positive alpha/beta T lymphocytes and a subset of natural killer (NK) cells. CD223 binds to MHC class II molecules with high affinity and is reported to negatively regulate T cell homeostasis and T cell expansion. Recognizes an epitope within the D2 domain of CD223. The antibody is reported to block the in vitro function of murine LAG-3 but studies suggest that the antibody does not block binding of LAG-3 to MHC class II. XXX recommend the use of MCA2386EL for this purpose.
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.

Packaging

Lyophilized, PBS, pH 7.4, 0.09% sodium azide, 1% BSA.
100 tst Distilled Water.
For research use only.

About LAG3

P18627 NM_002286 P18627

LAG3 Antibody, CD223 antigen Antibody, LAG-3 Antibody, Protein FDC Antibody, CD223 Antibody, FDC Antibody, Lymphocyte-activation gene 3 Antibody

Lymphocyte-Activation Protein 3 (LAG3) belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4.

Requested From: 
Date Requested: 8/21/2017

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