Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Human, Chimpanzee, Monkey, Rat, Bat, Horse, Pig, Rabbit, Chicken
Rabbit Polyclonal to Human LAF4 / AFF3
Human LAF4 / AFF3
Human (tested or 100% immunogen sequence identity)
Monkey, Bat, Bovine, Hamster, Pig, Rabbit (at least 90% immunogen sequence identity)
Protein G purified
Specificity and Use
LAF4 / AFF3 antibody was raised against synthetic peptide from human AFF3. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Marmoset, Hamster, Elephant, Panda, Bovine, Bat, Rabbit, Pig (94%); Mouse, Rat (88%); Chicken (81%).
KLH conjugated synthetic peptide comprising amino acids 1212 - 1227 [YSQQGLHWLRNSAHLS] of the human lymphoid nuclear protein related to AF4 (LAF4) protein.
PBS, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
AFF3 Antibody, AF4/FMR2 family member 3 Antibody, AF4/FMR2 family, member 3 Antibody, LAF4 Antibody, MLLT2-like Antibody, MLLT2-related protein Antibody, Lymphoid nuclear protein 4 Antibody, Protein LAF-4 Antibody
LAF4 / AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.