Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Guinea pig Polyclonal (IgG) to Human KRT84 / Keratin 84 / KRTHB4
IHC - Frozen, Western blot
Human KRT84 / Keratin 84 / KRTHB4
Human, Mouse (tested or 100% immunogen sequence identity)
IHC - Frozen (1:200)
Specificity and Use
KRT84 / Keratin 84 / KRTHB4 antibody was raised against basic hair keratin hHb4.
Recognizes human hair keratin hHb4 present starting from the upper layers of the filiform papillae of tongue epithelium and in mouse tail buds. No staining of anagen hair follicle. Species cross-reactivity: Mouse.
Suitable for use in Immunohistochemistry and Western Blot. Immunohistochemistry (Frozen): 1:200. Western Blot (ECL): 1:2000. Incubate at RT for 1 hour.
Serum, 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
KRT84 Antibody, Hard keratin, type II, 4 Antibody, HB4 Antibody, K84 Antibody, Keratin 84 Antibody, Keratin, type II cuticular Hb4 Antibody, Hb-4 Antibody, KRTHB4 Antibody, Type II hair keratin Hb4 Antibody, Keratin, hair, basic, 4 Antibody, Keratin-84 Antibody, Type II hair keratin 4 Antibody, Type-II keratin Kb24 Antibody
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5.