Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone BA17] (IgG1) to Human KRT19 / CK19 / Cytokeratin 19
IHC - Paraffin, IHC - Frozen, Western blot
Human KRT19 / CK19 / Cytokeratin 19
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [BA17]
IHC - Paraffin (1:50 - 1:100), IHC - Frozen, Western blot
Specificity and Use
KRT19 / CK19 / Cytokeratin 19 antibody was raised against mammary gland.
Recognizes the 40kD cytokeratin corresponding to cytokeratin 19. Cytokeratin 19 is expressed by many simple and non-keratinizing normal and neoplastic epithelia, including glandular and ductal epithelia.
Immunohistology: This product requires protein digestion pre-treatment of paraffin sections e. g. trypsin or pronase.
KRT19 / CK19 / Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells.