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Anti-KPNA1 / Importin Alpha 5 Antibody (clone 114-E12) LS-C16999

Ordering

Wt. Vol. Conc. Price
100 µg - - Unavailable

Most Popular KPNA1 / Importin Alpha 5 Antibodies

Anti-KPNA1 / Importin Alpha 5 Antibody (clone 2A4-1B5) IHC-plus™ LS-B6105
Mouse Monoclonal [clone 2A4-1B5] (IgG1,k) to Human KPNA1 / Importin Alpha 5
Human
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-KPNA1 / Importin Alpha 5 Antibody LS-C192816
Rabbit Polyclonal to Human KPNA1 / Importin Alpha 5
Human, Mouse, Rat
IHC, Western blot
Unconjugated
Western blot Image
Anti-KPNA1 / Importin Alpha 5 Antibody (aa1-539, AP) LS-C278673
Mouse Monoclonal (IgG1) to Human KPNA1 / Importin Alpha 5
Human
IHC, Western blot, ELISA
AP Conjugated
Anti-KPNA1 / Importin Alpha 5 Antibody (Biotin) LS-C318915
Rabbit Polyclonal (IgG) to Human KPNA1 / Importin Alpha 5
Human
ELISA
Biotin Conjugated
Anti-KPNA1 / Importin Alpha 5 Antibody LS-C331667
Rabbit Polyclonal (IgG) to Human KPNA1 / Importin Alpha 5
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone 114-E12] (IgG1) to Human KPNA1 / Importin Alpha 5
Human
Immunofluorescence, Western blot, Immunoprecipitation, ELISA (applications tested for the base form of this product only)
Unconjugated

Details

Human KPNA1 / Importin Alpha 5
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [114-E12]
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, MaxLight 405, MaxLight 490, MaxLight 550, MaxLight 650, MaxLight 750, PE.
Protein A purified
Unmodified

Applications

  • Immunofluorescence (5 - 10 µg/ml)
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

KPNA1 / Importin Alpha 5 antibody was raised against gST fusion protein.
Specific for the NPI-1 (nucleoprotein interactor-1, karyopherin alpha 1, hSRP1) protein. On Western blots, it identifies a band at ~60kD. Reactivity has been confirmed with human HeLa and MDBK cell lysates.
Suitable for use in Immunoprecipitation, Immunofluorescence, ELISA and Western Blot. Immunoprecipitation (native): 5-10 ug. Immunofluorescence: 5-10 ug/ml. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.

Packaging

PBS, pH 7.4, 0.1% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About KPNA1 / Importin Alpha 5

P52294 NM_002264 NP_002255.3

KPNA1 Antibody, Importin-alpha-S1 Antibody, Karyopherin subunit alpha-1 Antibody, NPI-1 Antibody, Importin alpha 5 Antibody, Importin subunit alpha-1 Antibody, SRP1 Antibody, SRP1-beta Antibody, RAG cohort protein 2 Antibody, Importin alpha-1 subunit Antibody, IPOA5 Antibody, Nucleoprotein interactor 1 Antibody, RCH2 Antibody

Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism.

Requested From: 
Date Requested: 4/27/2017

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