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KNG1 / Kininogen / Bradykinin
kininogen 1
1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
| Gene Name: | kininogen 1 |
| Synonyms: | KNG1, Bradykinin, Flaujeac factor deficiency, Fitzgerald factor, Kininogen 1, Kininogen-1, Kininogen, BDK, HMWK, KNG |
| Target Sequences: | NM_000893 NP_000884.1 P01042 |
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KNG1 / Kininogen / Bradykinin
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KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
200 µg/$672
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa1-416) Antibody
Human
ICC, IHC-P, WB
Unconjugated
50 µl/$440
Competitive EIA
96-Well Strip Plate
Human
1.23 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$764
Competitive EIA
96-Well Strip Plate
Mouse
1.23 - 100 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
Competitive EIA
96-Well Strip Plate
Rat
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Sandwich
96-Well Strip Plate
Mouse
0.25 - 16 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$818
Competitive EIA
96-Well Strip Plate
Rat
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (C11C1) Antibody
Human
ELISA, Neut, WB
Unconjugated
200 µg/$672
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Goat anti-Human Polyclonal (aa58-70) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (300-380 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Sandwich
96-Well Strip Plate
Monkey
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
E. coli
His-T7, N-terminus
43.9kDa
10 µg/$265; 50 µg/$347; 200 µg/$682; 100 µg/$545; 1 mg/$1,690; 500 µg/$1,270; 5 mg/$2,637; 2 mg/$1,866
KNG1 / Kininogen / Bradykinin Rabbit anti-Mouse Polyclonal (aa227-259) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
Competitive EIA
96-Well Strip Plate
Mouse
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Competitive EIA
96-Well Strip Plate
Rat
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (4A1) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
KNG1 / Kininogen / Bradykinin Goat anti-Human Polyclonal (aa268-279) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA
Unconjugated
400 µg/$878
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Viewing 1-25
of 184
product results
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