Target
Human KNG1 / Kininogen / Bradykinin
Synonyms
KNG1 | Bradykinin | Flaujeac factor deficiency | Fitzgerald factor | Kininogen 1 | Kininogen-1 | Kininogen | BDK | HMWK | KNG
Reactivity
Human
(tested or 100% immunogen sequence identity)
Specificity
Human KNG1 / Kininogen. The heavy chains in HMWK and LMWK share immunologic determinants, but they have no procoagulant activities. The light chain of HMWK is unique to this molecule and carries the entire procoagulant activity of the molecule. The antiserum does not distinct between different forms of kininogen. The presence of non-precipitating antibodies has not been assayed. /f the antiserum is to be used in non-precipitating antibody-binding assays (immunocytochemical, immunohistochemical, solid phase procedures such as EL/SA) proper controls should be included. No reaction is obtained with any other plasma protein component or serum Cross-reactivity The antiserum does not cross react with any other component of human plasma. /nter-species cross- reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail.