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KMT2E / MLL5

lysine (K)-specific methyltransferase 2E

Histone methyltransferase that specifically mono- and dimethylates 'Lys-4' of histone H3 (H3K4me1 and H3K4me2). H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Plays an essential role in retinoic-acid-induced granulopoiesis by acting as a coactivator of RAR-alpha (RARA) in target gene promoters. Also acts as an important cell cycle regulator, participating in cell cycle regulatory network machinery at multiple cell cycle stages. Required to suppress inappropriate expression of S-phase-promoting genes and maintain expression of determination genes in quiescent cells. Overexpression inhibits cell cycle progression, while knockdown induces cell cycle arrest at both the G1 and G2/M phases.Isoform NKp44L: Cellular ligand for NCR2/NKp44, may play a role as a danger signal in cytotoxicity and NK-cell-mediated innate immunity.

Gene Name: lysine (K)-specific methyltransferase 2E
Synonyms: KMT2E, Lysine N-methyltransferase 2E, MLL5, HDCMC04P
Target Sequences: NM_018682 NP_061152.3 Q8IZD2

☰ Filters
Antibodies (16)
Primary (16)
KMT2E / MLL5 (16)
Human (15)
Mouse (4)
Rat (2)
IHC (3)
WB (15)
ELISA (7)
ICC (1)
IF (3)
IP (4)
rabbit (15)
mouse (1)
IgG (11)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (11)
aa93-120 (7)
N-Terminus (1)
aa298-490 (1)
No (16)
KMT2E / MLL5 Antibody - Immunofluorescence analysis of U20S cells.
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KMT2E / MLL5 Antibody
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IP, WB
Unconjugated
50 µl/$286; 100 µl/$321
KMT2E / MLL5 Antibody - Western blot of KMT2E / MLL5 antibody
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa298-490) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
Select
KMT2E / MLL5 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) Antibody
Human
WB
Unconjugated
200 µl/$734
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
KMT2E / MLL5 Antibody - MLL5 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The MLL5 antibody detected the MLL5 protein (arrow).
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal (aa93-120) Antibody
Human
WB
Unconjugated
400 µl/$393
Select
KMT2E / MLL5 Rabbit anti-Human Polyclonal Antibody
Human
IP
Unconjugated
100 µl/$749
Select
KMT2E / MLL5 Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
Viewing 1-16 of 16 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).