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KMT2C / MLL3
lysine (K)-specific methyltransferase 2C
Histone methyltransferase. Methylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Central component of the MLL2/3 complex, a coactivator complex of nuclear receptors, involved in transcriptional coactivation. KMT2C/MLL3 may be a catalytic subunit of this complex. May be involved in leukemogenesis and developmental disorder.
| Gene Name: | lysine (K)-specific methyltransferase 2C |
| Synonyms: | KMT2C, ALR-like protein, HALR, Lysine N-methyltransferase 2C, MLL3, Homologous to ALR protein, KIAA1506 |
| Target Sequences: | NM_021230 NP_733751.2 Q8NEZ4 |
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