Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
KMT2A Antibody, ALL1 Antibody, CDK6/MLL fusion protein Antibody, FLJ11783 Antibody, HRX Antibody, HTRX Antibody, HTRX1 Antibody, Lysine N-methyltransferase 2A Antibody, MLL1A Antibody, MLL/GAS7 Antibody, MLL1 Antibody, ALL-1 Antibody, MLL Antibody, MLL/GAS7 fusion protein Antibody, TRX1 Antibody, WDSTS Antibody, Trithorax-like protein Antibody, Zinc finger protein HRX Antibody, CXXC7 Antibody, MLL-AF4 der(11) fusion protein Antibody, MLL/GMPS fusion protein Antibody, TET1-MLL Antibody
Histone methyltransferase that plays an essential role in early development and hematopoiesis. Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac). In the MLL1/MLL complex, it specifically mediates H3K4me, a specific tag for epigenetic transcriptional activation.
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
HRX Antibody flow cytometry of CEM cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.