Target
Human KMT2A / MLL
Synonyms
KMT2A | ALL1 | CDK6/MLL fusion protein | FLJ11783 | HRX | HTRX | HTRX1 | Lysine N-methyltransferase 2A | MLL1A | MLL/GAS7 | MLL1 | ALL-1 | MLL | MLL/GAS7 fusion protein | TRX1 | WDSTS | Trithorax-like protein | Zinc finger protein HRX | CXXC7 | MLL-AF4 der(11) fusion protein | MLL/GMPS fusion protein | TET1-MLL
Reactivity
Human, Mouse
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Immunogen
MBP fusion protein corresponding to residues 3084-3959 of human mixed lineage leukemia (MLL).
Specificity
Recognizes the C-terminal proteolytic fragment of human MLL (MLLC), Mr ~180kD. Species cross-reactivity: Human and mouse.
Applications
- Western blot (0.1 - 1 µg/ml)
- Immunoprecipitation
Usage
Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: Reported by an independent laboratory to immunoprecipitate MLLC from nuclear extracts. The N-terminal fragment, MLLN (300kD), is also co-immunoprecipitated by this antibody.
Presentation
0.1 M Tris-Glycine, pH 7.4, 0.15 M NaCl, 0.05% Sodium Azide, 30% Glycerol
Storage
Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee