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Anti-KMO Antibody (aa155-182) LS-C165595

Ordering

Wt. Vol. Conc. Price
- 400 µl - Unavailable

Most Popular KMO Antibodies

Anti-KMO Antibody (aa155-182) LS-C165595
Rabbit Polyclonal to Human KMO
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-KMO Antibody (aa1-260) LS-C376014
Rabbit Polyclonal (IgG) to Human KMO
Human, Mouse
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-KMO Antibody (aa1-282, Biotin) LS-C424564
Rabbit Polyclonal (IgG) to Rat KMO
Rat
IHC - Paraffin, IHC - Frozen, ICC, Western blot, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human KMO
Human
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated

Details

Human KMO
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Protein A purified
Unmodified

Applications

  • IHC - Paraffin (1:10 - 1:50)
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)

Specificity and Use

LS-E9708 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C165595. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
aa155-182
This KMO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 155-182 amino acids from the Central region of human KMO.

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About KMO

O15229 NM_003679 NP_003670.2

KMO Antibody, DJ317G22.1 Antibody, Kynurenine 3-hydroxylase Antibody, Kynurenine 3-monooxygenase Antibody

Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with KMO Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Western blot

Western blot
Western blot of KMO Antibody in CEM cell line lysates (35 ug/lane). KMO (arrow) was detected using the purified antibody.

Flow Cytometry

Flow Cytometry
KMO Antibody flow cytometry of CEM cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
 

Requested From: 
Date Requested: 3/24/2017

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