KLRK1 / CD314 / NKG2D

killer cell lectin-like receptor subfamily K, member 1

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.

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Products

Antibodies (62)

Proteins (11)

ELISA Kits (1)

Type

Primary (62)

Recombinant (11)

Sandwich (1)

Target

KLRK1 / CD314 / NKG2D (74)

Reactivity

Human (45)

Mouse (16)

Rat (12)

Bovine (6)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Monkey (4)

Orangutan (6)

Application

IHC (7)

IHC-Fr (9)

IHC-P (1)

WB (41)

Flo (13)

ELISA (9)

Func (6)

IF (3)

IP (9)

Peptide-ELISA (3)

Host

rabbit (47)

mouse (13)

goat (1)

rat (1)

Product Group

IHCPlus (1)

Isotype

IgG (13)

IgG1 (12)

IgG1,k (1)

IgG3 (1)

Clonality

monoclonal mc (14)

polyclonal pc (48)

Clone

02 (1)

1D11 (12)

CX5 (1)

Format

96-Well Microplate (1)

APC (3)

APC Conjugated (4)

Azide-free (1)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (8)

HRP Conjugated (6)

Low Endotoxin (2)

PE Conjugated (5)

Preservative Free (1)

RPE Conjugated (1)

Unconjugated (26)

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Epitope

aa75-215 (8)

aa90-232 (8)

aa92-216 (8)

C-Terminus (4)

aa121-170 (4)

80-160 aa, Internal (1)

aa111-160 (1)

aa136-147 (1)

Publications

No (74)

Sample Type

Cell Culture Supernatants (1)

Plasma (1)

Serum (1)

Tag

6His, N-terminus (4)

Fc, N-terminus (1)

GST (1)

His (2)

His-T7 (2)

Species

Cynomolgus (1)

Human (8)

Mouse (1)

Rat (1)

Source

Baculovirus (1)

E. coli (4)

Human (2)

Human Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (6)

Select

KLRK1 / CD314 / NKG2D Antibody (C-Terminus) LS-B14033

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C123953

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (1D11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IP

Format:

Unconjugated

Price:

200 µg/$732

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11, Azide-free) LS-C204360

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (Azide-free) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC-Fr, IP

Format:

Unconjugated, Azide-free

Price:

0.1 mg/$302

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Mouse KLRK1 / CD314 / NKG2D Protein (Recombinant 6His, N-terminus) (aa90-232) - LS-G24467

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

20.1 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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KLRK1 / CD314 / NKG2D Antibody (aa90-232) LS-C374220

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Mouse Polyclonal (aa90-232) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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Human KLRK1 / CD314 / NKG2D (Sandwich ELISA) ELISA Kit - LS-F50251

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.4 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$672

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KLRK1 / CD314 / NKG2D Antibody LS-C499208

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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Rat KLRK1 / CD314 / NKG2D Protein (Recombinant His-T7) (aa75-215) - LS-G24468

Source:

E. coli

Tag:

His-T7

Molecular Weight:

19.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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KLRK1 / CD314 / NKG2D Antibody LS-C805679

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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KLRK1 / CD314 / NKG2D Antibody (aa136-147) LS-C20184

Antibody:

KLRK1 / CD314 / NKG2D Goat anti-Human Polyclonal (aa136-147) Antibody

Reactivity:

Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C204311

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC, IHC-Fr, IP

Format:

Unconjugated

Price:

0.1 mg/$302

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11, FITC) LS-C204417

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (FITC) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC-Fr, IP

Format:

FITC Conjugated

Price:

100 Tests/$337

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11, APC) LS-C204393

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (APC) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC-Fr, IP

Format:

APC Conjugated

Price:

100 Tests/$365

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11, PE) LS-C204454

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (PE) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC-Fr, IP

Format:

PE Conjugated

Price:

100 Tests/$365

• Unconjugated
• FITC
• APC
• PE

• Unconjugated
• FITC
• APC
• More...
  • PE

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KLRK1 / CD314 / NKG2D Antibody (clone CX5) LS-C106909

Antibody:

KLRK1 / CD314 / NKG2D Rat anti-Mouse Monoclonal (CX5) Antibody

Reactivity:

Mouse

Applications:

Flo

Format:

Unconjugated

Price:

50 µg/$285

Select

KLRK1 / CD314 / NKG2D Antibody (clone 1D11) LS-C44803

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (1D11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-Fr, IP

Format:

Unconjugated

Price:

0.2 mg/$471

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KLRK1 / CD314 / NKG2D Antibody (clone 1D11, Low Endotoxin) LS-C123954

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (Low Endotoxin) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, Func, IHC, IHC-Fr, IP

Format:

Unconjugated, Low Endotoxin

Price:

500 µg/$968

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Human KLRK1 / CD314 / NKG2D Protein (Recombinant 6His, N-terminus) (Phe78-Val216) - LS-G40284

Source:

Human Cells

Tag:

6His, N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

16.9kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

Select

Human KLRK1 / CD314 / NKG2D Protein (Recombinant His) - LS-G2035

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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KLRK1 / CD314 / NKG2D Antibody LS-C813812

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

KLRK1 / CD314 / NKG2D Antibody (clone 1D11, Low Endotoxin) LS-C44804

Antibody:

KLRK1 / CD314 / NKG2D Mouse anti-Human Monoclonal (Low Endotoxin) (1D11) Antibody

Reactivity:

Human

Applications:

Flo, IHC-Fr, IP

Format:

Unconjugated, Low Endotoxin

Price:

0.5 mg/$671

Select

KLRK1 / CD314 / NKG2D Antibody (80-160 aa, Internal) LS-C382539

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

KLRK1 / CD314 / NKG2D Antibody LS-C824950

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

KLRK1 / CD314 / NKG2D Antibody (aa111-160) LS-C291454

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal (aa111-160) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

KLRK1 / CD314 / NKG2D Antibody LS-C832911

Antibody:

KLRK1 / CD314 / NKG2D Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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