Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human KLRK1 / CD314 / NKG2D
IHC, Immunofluorescence, ELISA
Mouse Monoclonal [clone 1D11] (IgG1) to Human KLRK1 / CD314 / NKG2D
Human KLRK1 / CD314 / NKG2D
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1D11]
Protein A purified
Specificity and Use
NKL cell line.
Monoclonal antibody 1D11 recognizes CD314 / NKG2D, a 42 kD C-type lectin-like activating receptor expressed by NK cells, gamma/delta T cells, and CD8+ T cells.
The reagent is designed for Flow Cytometry analysis of human blood cells using 4 ul reagent / 100 ul of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, 0.2% BSA, 0.02% sodium azide.
Store in the dark at 2-8 C. Do not freeze. Avoid prolonged exposure to light.
KLRK1 Antibody, D12S2489E Antibody, CD314 antigen Antibody, KLR Antibody, NK cell receptor D Antibody, NKG2D Antibody, NKG2-D Antibody, NKG2-D-activating NK receptor Antibody, CD314 Antibody
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells.