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Anti-KLRB1 / CD161 Antibody (clone B199.2, PE) LS-C14358

Ordering

Wt. Vol. Conc. Price
- 100 tst - $495
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular KLRB1 / CD161 Antibodies

Anti-KLRB1 / CD161 Antibody (clone B199.2, Biotin) LS-C35855
Mouse Monoclonal [clone B199.2] (IgG2b) to Human KLRB1 / CD161
Human
Flow Cytometry
Biotin Conjugated
Anti-KLRB1 / CD161 Antibody (clone B199.2) LS-C123172
Mouse Monoclonal [clone B199.2] (IgG2b) to Human KLRB1 / CD161
Human
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Unconjugated
Anti-KLRB1 / CD161 Antibody (aa68-225, clone 14F1F11) LS-C359302
Mouse Monoclonal [clone 14F1F11] (IgG1,k) to Human KLRB1 / CD161
Human
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone B199.2] (IgG2b) to Human KLRB1 / CD161
Human
Flow Cytometry
PE Conjugated

Details

Human KLRB1 / CD161
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [B199.2]
Phycoerythrin
Protein G purified
Unmodified

Applications

Flow Cytometry

Specificity and Use

Recognizes the human CD161 cell surface antigen, expressed by almost all NK cells and with a small subset of CD3+ve T cells. CD161 is a homodimeric cell surface protein, comprising two chains of 40-44kD. Clone 3H1911 recognizes a similar epitope to the DX9 monoclonal antibody.
Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

Lyophilized from PBS, pH 7.2, 0.1% sodium azide, 1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About KLRB1 / CD161

Q12918 NM_002258 NP_002249.1

KLRB1 Antibody, CD161 antigen Antibody, CLEC5B Antibody, CD161 Antibody, NKR-P1A Antibody, NKR Antibody, HNKR-P1A Antibody, NKR-P1 Antibody, NKRP1A Antibody

Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope.

Requested From: United States
Date Requested: 12/5/2016

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