Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human KLKB1 / Plasma Kallikrein
Mouse Monoclonal [clone 13G11] (IgG1) to Human KLKB1 / Plasma Kallikrein
Western blot, ELISA
Human KLKB1 / Plasma Kallikrein
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [13G11]
Protein G purified
Specificity and Use
Purified human prekallikrein.
Recognizes two variants (88 kD and 85 kD) of prekallikrein and its activation products kallikrein (88 kD and 85 kD), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kD prekallikrein/kallikrein fragment (s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. does not cross-react with tissue kallikrein.
Suitable for use in ELISA and Western Blot.
PBS, pH 7.4, contains no preservative.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Plasma prekallikrein is a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. It is synthesized in the liver and secreted into the blood as a single polypeptide chain. Plasma prekallikrein is converted to plasma kallikrein by factor XIIa by the cleavage of an internal Arg-Ile bond. Plasma kallikrein therefore is composed of a heavy chain and a light chain held together by a disulphide bond.