Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human KLK13 / Kallikrein 13
Rabbit Polyclonal to Human KLK13 / Kallikrein 13
Human KLK13 / Kallikrein 13
Human (tested or 100% immunogen sequence identity)
Western blot (1:500 - 1:1000)
Specificity and Use
Peptide corresponding to aa 262-277 of human KLK13 protein.
Recognizes the gene product hk13 of human KLK13 (also known as KLK-L4), one of the many kallikrein serine proteases associated with carcinogenesis. KLK13 is up- regulated by steroid hormones and is expressed in prostate, salivary gland, breast, and testis.
Western Blot: A band of approximately 30 kD is detected.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer.