KLHL25

kelch-like family member 25

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.

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Products

Antibodies (30)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (30)

Recombinant (1)

Target

KLHL25 (33)

Reactivity

Human (30)

Mouse (6)

Rat (6)

Bat (6)

Bovine (3)

Chicken (3)

Chimpanzee (9)

Dog (9)

Gibbon (9)

Guinea pig (6)

Hamster (9)

Monkey (6)

Pig (9)

Rabbit (3)

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Application

IHC (13)

IHC-P (14)

WB (29)

ELISA (15)

ICC (2)

IF (2)

Host

rabbit (20)

mouse (9)

chicken (1)

Product Group

IHCPlus (3)

Isotype

IgG (15)

IgG2a,k (6)

IgG2b (3)

IgY (1)

Clonality

monoclonal mc (9)

polyclonal pc (21)

Clone

1B7 (2)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (5)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (2)

Unconjugated (11)

Epitope

aa62-91 (7)

aa144-193 (4)

aa163-212 (4)

aa68-117 (4)

Publications

No (33)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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IHC-plus™ KLHL25 Antibody LS-B5090

(4.0) Rating

Antibody:

KLHL25 Chicken anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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KLHL25 Antibody (aa68-117) LS-B12583

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa68-117) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

KLHL25 Antibody (aa68-117, HRP) LS-C431332

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa68-117) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

KLHL25 Antibody (aa68-117, Biotin) LS-C431330

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa68-117) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

KLHL25 Antibody (aa68-117, FITC) LS-C431331

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa68-117) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KLHL25 Antibody (aa144-193) LS-B12584

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa144-193) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

Select

KLHL25 Antibody (aa144-193, HRP) LS-C431895

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa144-193) (HRP) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

KLHL25 Antibody (aa144-193, Biotin) LS-C431893

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa144-193) (Biotin) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

KLHL25 Antibody (aa144-193, FITC) LS-C431894

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa144-193) (FITC) Antibody

Reactivity:

Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KLHL25 Antibody LS-C816603

Antibody:

KLHL25 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC-P

Format:

Unconjugated

Price:

100 µl/$412

Select

KLHL25 Antibody (aa163-212) LS-C31795

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa163-212) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

Select

KLHL25 Antibody (aa163-212, HRP) LS-C431476

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa163-212) (HRP) Antibody

Reactivity:

Chicken, Rabbit, Dog, Hamster, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

KLHL25 Antibody (aa163-212, Biotin) LS-C431474

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa163-212) (Biotin) Antibody

Reactivity:

Chicken, Rabbit, Dog, Hamster, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

KLHL25 Antibody (aa163-212, FITC) LS-C431475

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa163-212) (FITC) Antibody

Reactivity:

Chicken, Rabbit, Dog, Hamster, Pig, Gibbon, Chimpanzee, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KLHL25 Antibody LS-C308668

Antibody:

KLHL25 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

KLHL25 Antibody (HRP) LS-C542872

Antibody:

KLHL25 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

KLHL25 Antibody (Biotin) LS-C522740

Antibody:

KLHL25 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

KLHL25 Antibody (FITC) LS-C532784

Antibody:

KLHL25 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

KLHL25 Antibody (PE) LS-C650984

Antibody:

KLHL25 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

KLHL25 Antibody (APC) LS-C514526

Antibody:

KLHL25 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

KLHL25 Antibody (clone 1B7) LS-C169216

Antibody:

KLHL25 Mouse anti-Human Monoclonal (1B7) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$435

Select

KLHL25 Antibody LS-C812681

Antibody:

KLHL25 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

KLHL25 Antibody (aa62-91) LS-C322525

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa62-91) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

KLHL25 Antibody (aa62-91, Azide-free, HRP) LS-C223003

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa62-91) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

KLHL25 Antibody (aa62-91, APC) LS-C222999

Antibody:

KLHL25 Rabbit anti-Human Polyclonal (aa62-91) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP, Azide-free
• APC

• Unconjugated
• HRP, Azide-free
• APC

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