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| Catalog Number | Size | Price |
|---|---|---|
| LS-B3568-50 | 50 µl (0.5 mg/ml) | $460 |
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Polyclonal Rabbit anti‑Human KLB / Beta Klotho Antibody (Internal, IHC, WB) LS‑B3568
Polyclonal Rabbit anti‑Human KLB / Beta Klotho Antibody (Internal, IHC, WB) LS‑B3568
Note: This antibody replaces LS-C82738
Antibody:
KLB / Beta Klotho Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
KLB / Beta Klotho Rabbit anti-Human Polyclonal (Internal) Antibody
Application:
IHC, IHC-P, WB
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Beta Klotho antibody LS-B3568 is an unconjugated rabbit polyclonal antibody to human Beta Klotho (KLB) (Internal). Validated for IHC and WB. Cited in 5 publications.
Target
Human KLB / Beta Klotho
Synonyms
KLB | BetaKlotho | Beta-klotho | BKL | Klotho beta | Klotho beta like | Klotho beta-like protein
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from internal region of human KLB (NP_783864.1, Q86Z14). Percent identity by BLAST analysis: Human (100%); Dog, Horse (92%); Rabbit, Chicken (85%); Guinea pig (84%).
Epitope
Internal
Specificity
Human KLB
Applications
- IHC
- IHC - Paraffin (10 µg/ml)
- Western blot (0.5 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
LSBio Ratings
KLB / Beta Klotho Antibody (Internal) for IHC, WB/Western LS-B3568 has an LSBio Rating of
Publications (4.4)
Learn more about The LSBio Ratings Algorithm
Publications (5)
Screen for small molecules increasing the mitochondrial membrane potential. Montague CR, Fitzmaurice A, Hover BM, Salazar NA, Fey JP. Journal of biomolecular screening. 2014 Mar;19:387-98.
MicroRNA 34a inhibits beige and brown fat formation in obesity in part by suppressing adipocyte fibroblast growth factor 21 signaling and SIRT1 function. Fu T, Seok S, Choi S, Huang Z, Suino-Powell K, Xu HE, Kemper B, Kemper JK. Molecular and cellular biology. Nov;34:4130-42.
Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor beta -Klotho. Fu T, Choi SE, Kim DH, Seok S, Suino-Powell KM, Xu HE, Kemper JK. Proceedings of the National Academy of Sciences of the United States of America. Oct;109:16137-42.
Ileal Transposition Surgery Decreases Fat Mass and Improves Glucose Metabolism in Diabetic GK Rats: Possible Involvement of FGF21. Yan K, Chen W, Zhu H, Lin G, Pan H, Li N, Wang L, Yang H, Liu M, Gong F. Frontiers in physiology. 2018 March;9:191. (Human)
Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake. Pineda C, Rios R, Raya AI, Rodriguez M, Aguilera-Tejero E, Lopez I. Nutrients. 2018 October;10:pii E1496.
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Featured Products
Species:
Human, Mouse
Applications:
Western blot
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot
Reactivity:
Human
Range:
15.6-1000 pg/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/17/2024
Date Requested: 4/17/2024
