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KISS1 / Kisspeptin / Metastin

KiSS-1 metastasis-suppressor

Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca2+ levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.

Gene Name: KiSS-1 metastasis-suppressor
Synonyms: KISS1, HH13, Metastasis-suppressor KiSS-1, Kisspeptin-1, Metastin, KiSS-1, KiSS-1 metastasis-suppressor
Target Sequences: NM_002256 NP_002247.3 Q15726

☰ Filters
Antibodies (55)
ELISA Kits (17)
Proteins (8)
Competitive EIA (4)
Development Kit (1)
Over-Expression Lysate (2)
Primary (55)
Recombinant (6)
Sandwich (12)
KISS1 / Kisspeptin / Metastin (80)
Human (45)
Mouse (15)
Rat (14)
Bovine (1)
Cow (1)
IHC (5)
IHC-P (3)
WB (47)
ELISA (10)
ICC (10)
IF (2)
IP (8)
Peptide-ELISA (1)
rabbit (46)
mouse (9)
Product Group
DevKit DuoPlus (1)
IHCPlus (2)
IgG (17)
IgG1,k (8)
IgG2a,k (1)
monoclonal mc (9)
polyclonal pc (46)
1F7 (1)
96-Well Strip Plate (16)
Antibody Pair and Standard (1)
APC (4)
APC Conjugated (5)
Biotin Conjugated (6)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (5)
Unconjugated (19)
aa1-126 (8)
Internal (1)
N-Terminus (1)
aa112-121 (1)
aa115-145 (1)
aa20-138 (1)
aa20-52 (1)
aa68-121 (1)
aa68-92 (1)
aa94-121 (1)
pTyr112 (1)
No (80)
Cell Culture Supernatants (1)
Cell Lysates (2)
Cell Supernatant (1)
Plasma (17)
Serum (17)
Tissue Homogenates (6)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-GST (1)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
KISS1 / Kisspeptin / Metastin Antibody - 1:100 staining mouse testis tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KISS1 / Kisspeptin / Metastin Antibody - Western blot of KISS1 expression in transfected 293T cell line by KISS1 monoclonal antibody (M05), clone 1F7.
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KISS1 / Kisspeptin / Metastin Mouse anti-Human Monoclonal (1F7) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (pTyr112) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
KISS1 / Kisspeptin / Metastin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$834
KISS1 / Kisspeptin / Metastin ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
KISS1 / Kisspeptin / Metastin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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KISS1 / Kisspeptin / Metastin Mouse anti-Human Monoclonal Antibody
Human
ICC, IHC-P, WB
Unconjugated
50 µl/$460
KISS1 / Kisspeptin / Metastin ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
KISS1 / Kisspeptin / Metastin Antibody - Western blot of KISS1 / Kisspeptin / Metastin antibody using a recombinant protein encoding aa 1-126 with a His and GST tag.
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KISS1 / Kisspeptin / Metastin Rabbit anti-Mouse Polyclonal (aa1-126) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
KISS1 / Kisspeptin / Metastin Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (aa20-138) Antibody
Human
ICC, IHC-P, IP, WB
Unconjugated
50 µl/$460
KISS1 / Kisspeptin / Metastin Protein - Recombinant  Kisspeptin 1 By SDS-PAGE
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E. coli
His-GST
46.1 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
KISS1 / Kisspeptin / Metastin ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$854
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
24.69 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$893
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, ICC, WB
Unconjugated
100 µl/$440; 200 µl/$468
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
KISS1 / Kisspeptin / Metastin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
KISS1 / Kisspeptin / Metastin Antibody - Immunohistochemistry image of paraffin-embedded human liver cancer at a dilution of 1:100
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ICC, IP, WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
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KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Select
KISS1 / Kisspeptin / Metastin Rabbit anti-Human Polyclonal (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
Viewing 1-25 of 80 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).