Human KIR2DL3 / CD152B2

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

GL183

Unconjugated

Purified

Unmodified

NK cell clone E57.

Extracellular Domain

Recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

• Immunoprecipitation
• Flow Cytometry (1:10 - 1:50)

Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: 1:10-1:50. Use 10 ul to label 1E6 cells in 100ul.

PBS, pH 7.2, 0.09% Sodium Azide

Short term: store at 4°C. Long term: store at -20°C. Avoid freeze-thaw cycles.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

NCBI: NM_014511 NP_055326.3