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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Kinesin Heavy Chain / KIF5B Antibody (aa951‑963) IHC‑plus™ LS‑B2489
Note: This antibody replaces LS-C34646, LS-C71382, LS-C71350
KIF5B antibody LS-B2489 is an unconjugated goat polyclonal antibody to KIF5B (Kinesin Heavy Chain) from human, bovine, dog and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
Catalog
Size
Price
LS-B2489-50
50 µg (0.5 mg/ml)
Unavailable

Popular Kinesin Heavy Chain / KIF5B Products

Antibody
Species: Bovine, Chicken, Mammal, Sea urchin, Squid
Applications: IHC, ICC, Western blot, Immunoprecipitation, ELISA, Radioimmunoassay
Anti-KIF5B antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4501 concentration 10 ug/ml.
Species: Pig, Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Bovine, Dog
Applications: IHC, IHC - Paraffin, Western blot
Antibody
Species: Bovine, Chicken, Mammal
Applications: IHC, ICC, Western blot, Immunoprecipitation, ELISA, Radioimmunoassay

Product Description

KIF5B antibody LS-B2489 is an unconjugated goat polyclonal antibody to KIF5B (Kinesin Heavy Chain) from human, bovine, dog and other species. Validated for IHC, Peptide-ELISA and WB. Tested on 20 paraffin-embedded human tissues. Cited in 2 publications.
About Kinesin Heavy Chain / KIF5B
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. P33176 NM_004521 NP_004512.1

KIF5B Antibody, Kinesin 1 (110-120kD) Antibody, KINH Antibody, KNS Antibody, Kinesin family member 5B Antibody, Kinesin heavy chain Antibody, KNS1 Antibody, UKHC Antibody, Kinesin-1 heavy chain Antibody, Ubiquitous kinesin heavy chain Antibody


Specifications

Target
Human Kinesin Heavy Chain / KIF5B
Host
Goat
Reactivity
Human, Monkey, Bovine, Dog, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Horse (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:32000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Synthetic peptide C-QPVAVRGGGGKQV from the C-terminus of human KIF5B (NP_004512.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bovine, Rabbit, Pig (100%); Elephant, Panda, Horse (92%); Turkey, Platypus (85%).
Blocking Peptide
LS-E25378 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-B2489. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa951-963
Specificity
Human KIF5B.
Usage
Immunohistochemistry: LS-B2489 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2489 was determined to be 2.5 ug/ml.
Presentation
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (2)

1
Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport. Gupta V, Palmer KJ, Spence P, Hudson A, Stephens DJ. Traffic (Copenhagen, Denmark). 2008 9:1850-66. [PubMed:18817524]
2
KIF5C, a kinesin motor involved in apical trafficking of MDCK cells. Astanina K, Jacob R. Cellular and molecular life sciences : CMLS. 2010 67:1331-42. [PubMed:20094756]

Customer Reviews (0)


Images


Immunohistochemistry

Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.
Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.

Immunohistochemistry

Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.
Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.

Immunohistochemistry

Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.
Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.

Immunohistochemistry

Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.
Anti-KIF5B antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2489 concentration 5 ug/ml.


Requested From: 
Date Requested: 6/24/2018

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