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Anti-KEAP1 Antibody (C-Terminus) IHC-plus™ LS-B8871

Note: This antibody replaces LS-C153657

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KEAP1 Antibodies

Anti-KEAP1 Antibody (aa41-53) IHC-plus™ LS-B8363
Goat Polyclonal to Human KEAP1
Human, Monkey, Bat, Bovine, Dog, Horse, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-KEAP1 Antibody (clone 1B4) LS-C172468
Mouse Monoclonal [clone 1B4] (IgG1) to Human KEAP1
Human, Mouse
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-KEAP1 Antibody (C-Terminus) IHC-plus™ LS-B8871
Rabbit Polyclonal to Human KEAP1
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human KEAP1
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human KEAP1
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (2.5 µg/ml)
  • Western blot (1 - 2 µg/ml)

Specificity and Use

KEAP1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human KEAP1.
LS-E31339 - Liquid - 50 µg - $145.00
C-Terminus
Human KEAP1. At least two isoforms of KEAP1 are known to exist.
KEAP1 antibody can be used for detection of KEAP1 by Western blot at 1-2 ug/mL.

Packaging

PBS, 0.02% sodium azide
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About KEAP1

Q14145 NM_012289 NP_036421.2

KEAP1 Antibody, Cytosolic inhibitor of Nrf2 Antibody, INrf2 Antibody, KLHL19 Antibody, Kelch-like protein 19 Antibody, KIAA0132 Antibody

Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

Immunohistochemistry

Immunohistochemistry
Anti-KEAP1 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunofluorescence

Immunofluorescence
Immunofluorescence of KEAP1 in human lung tissue with KEAP1 antibody at 20 ug/ml.

Western blot

Western blot
Western blot analysis of KEAP1 in human lung tissue lysate with KEAP1 antibody at (A) 1 and (B) 2 ug/ml.
 

Requested From: United States
Date Requested: 12/4/2016

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