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Anti-KEAP1 Antibody (aa21-70) IHC-plus™ LS-B5612

Note: This antibody replaces LS-C30394

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $450
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KEAP1 Antibodies

Anti-KEAP1 Antibody (aa41-53) IHC-plus™ LS-B8363
Goat Polyclonal to Human KEAP1
Human, Monkey, Bat, Bovine, Dog, Horse, Pig
IHC - Paraffin, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-KEAP1 Antibody (clone 1B4) LS-C172468
Mouse Monoclonal [clone 1B4] (IgG1) to Human KEAP1
Human, Mouse
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-KEAP1 Antibody (C-Terminus) IHC-plus™ LS-B8871
Rabbit Polyclonal to Human KEAP1
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human KEAP1
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Zebrafish
IHC - Paraffin, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human KEAP1
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Pig, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with FITC, Biotin, HRP.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • Western blot (0.2 - 1 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

KEAP1 antibody was raised against synthetic peptide located between aa21-70 of human KEAP1 (Q14145, NP_987096). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bovine, Bat, Horse, Pig, Opossum, Lizard (100%); Platypus (92%).
LS-E12358 - Lyophilized - 100 µg - $145.00
aa21-70
Human KEAP1

Packaging

Lyophilized from PBS with 2% sucrose
50 µl After adding water, will consist of PBS buffer with 2% sucrose
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About KEAP1

Q14145 NM_012289 NP_036421.2

KEAP1 Antibody, Cytosolic inhibitor of Nrf2 Antibody, INrf2 Antibody, KLHL19 Antibody, Kelch-like protein 19 Antibody, KIAA0132 Antibody

Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

Immunohistochemistry

Immunohistochemistry
Anti-KEAP1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5612 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
Transfected Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/10/2016

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