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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KDR / VEGFR2 / FLK1 Antibody (Internal, DY488) LS‑C141216
FLK1 antibody LS-C141216 is a DY488-conjugated rabbit polyclonal antibody to FLK1 (KDR / VEGFR2) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C141216-100
100 µl
Unavailable

Popular KDR / VEGFR2 / FLK1 Products

Anti-KDR / VEGFR2 antibody IHC of human Breast, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Anti-VEGFR2 antibody IHC of human placenta, endothelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B669 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Formalin-fixed, paraffin-embedded human angiosarcoma stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of tumor cells.  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Antibody
Species: Human
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot

Product Description

FLK1 antibody LS-C141216 is a DY488-conjugated rabbit polyclonal antibody to FLK1 (KDR / VEGFR2) from human, mouse and rat. Validated for WB.
About KDR / VEGFR2 / FLK1
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and differentiation of endothelial cells. Promotes reorganization of the actin cytoskeleton. Isoforms lacking a transmembrane domain, such as isoform 2 and isoform 3, may function as decoy receptors for VEGFA, VEGFC and/or VEGFD. P35968 NM_002253 NP_002244.1

KDR Antibody, CD309 Antibody, Fetal liver kinase 1 Antibody, Fetal liver kinase-1 Antibody, FLK-1 Antibody, FLK1 Antibody, Kinase insert domain receptor Antibody, Quek1 Antibody, VEGFR Antibody, VEGFR2 Antibody, Soluble VEGFR2 Antibody, VEGF receptor 2 Antibody, VEGFR-2 Antibody, CD309 antigen Antibody, VEGF-R2 Antibody


Specifications

Target
Human KDR / VEGFR2 / FLK1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Western blot (1:250 - 1:1000)
  • (applications tested for the base form of this product only)
Immunogen
A synthetic peptide made to an internal region of the murine VEGFR2 protein sequence (between residues 1200-1300) Percent identity by BLAST analysis: Mouse, Rat, Human (100%).
Epitope
Internal
Specificity
VEGR-2.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in VEGFR-2 induced HUVEC lysate (50 ug) using LS-C2933 (4 ug/ml). ECL detection 2.5 minutes. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of VEGFR-2 doublet in CSF-1 receptor/VEGFR2 chimera transfected lysate (20 ug) using LS-C2933 (6 ug/ml). ECL detection 30 seconds. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/23/2018

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