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KDM6B / JMJD3

lysine (K)-specific demethylase 6B

Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

Gene Name: lysine (K)-specific demethylase 6B
Synonyms: KDM6B, JMJD3, Jumonji domain containing 3, Lysine-specific demethylase 6B, KIAA0346, Lysine demethylase 6B
Target Sequences: AB002344 BAA21572.2 O15054

Publications (3)

1
Epigenetic reprogramming during wound healing: loss of polycomb-mediated silencing may enable upregulation of repair genes. Shaw T, Martin P. EMBO reports. 2009 10:881-6. [PubMed:19575012] [PMC:PMC2726669]
2
Epithelial cell adhesion molecule regulation is associated with the maintenance of the undifferentiated phenotype of human embryonic stem cells. Lu TY, Lu RM, Liao MY, Yu J, Chung CH, Kao CF, Wu HC. The Journal of biological chemistry. 2010 285:8719-32. [PubMed:20064925] [PMC:PMC2838295] Related Antibodies: LS-C96527.
3
Evidence for alteration of EZH2, BMI1, and KDM6A and epigenetic reprogramming in human papillomavirus type 16 E6/E7-expressing keratinocytes. Hyland PL, McDade SS, McCloskey R, Dickson GJ, Arthur K, McCance DJ, Patel D. Journal of virology. 2011 85:10999-1006. [PubMed:21865393] [PMC:PMC3194988] Related Antibodies: LS-C96527.

☰ Filters
Antibodies (36)
ELISA Kits (1)
Primary (36)
Sandwich (1)
KDM6B / JMJD3 (37)
Human (36)
Mouse (19)
Rat (7)
Bat (3)
Bovine (6)
Chimpanzee (6)
Dog (6)
Guinea pig (3)
Horse (6)
Monkey (6)
Pig (3)
Rabbit (6)
IHC (7)
IHC-P (1)
WB (32)
ELISA (15)
ICC (4)
IF (8)
Peptide-ELISA (3)
rabbit (36)
IgG (28)
polyclonal pc (36)
96-Well Microplate (1)
APC Conjugated (2)
Biotin Conjugated (6)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (2)
Unconjugated (13)
aa1-30 (7)
aa954-987 (6)
Internal (5)
N-Terminus (4)
aa1613-1662 (4)
aa1023-1057 (1)
aa879-912 (1)
No (36)
Yes (1)
Cell Lysates (1)
Tissue Homogenates (1)
KDM6B / JMJD3 Antibody - Immunocytochemistry of JMJD3 in K562 cells with JMJD3 antibody at 2.5 ug/ml.
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, ICC, IF, WB
Unconjugated
0.1 mg/$460
KDM6B / JMJD3 Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with JMJD3 , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
200 µl/$393
KDM6B / JMJD3 Antibody - KDM6B / JMJD3 antibody Western blot of Fetal Lung lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDM6B / JMJD3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
KDM6B / JMJD3 Antibody - Immunofluorescent analysis of Hela cells at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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KDM6B / JMJD3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal (aa954-987) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa954-987) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa954-987) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa954-987) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa954-987) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa954-987) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
KDM6B / JMJD3 Antibody - Anti-KDM6B Antibody at 1:2000 dilution + mouse lung lysates Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 177 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa879-912) Antibody
Mouse
Peptide-ELISA, WB
Unconjugated
400 µl/$393
KDM6B / JMJD3 Antibody - Western blot analysis of extracts of mouse brain tissue using JMJD3 antibody. The lane on the left was treated with blocking peptide.
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KDM6B / JMJD3 Antibody - JMJD3 Antibody - Western Blot on HepG2 cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal (Internal) Antibody
Mouse, Human
WB
Unconjugated
0.1 ml/$386
KDM6B / JMJD3 Antibody - JMJD3 Antibody - Western Blot on HepG2 cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal (Internal) (Biotin) Antibody
Mouse, Human
WB
Biotin Conjugated
0.1 ml/$416
KDM6B / JMJD3 Antibody - JMJD3 Antibody - Western Blot on HepG2 cell lysates.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal (Internal) (DY650) Antibody
Mouse, Human
WB
DY650 Conjugated
0.1 ml/$416
KDM6B / JMJD3 Antibody - Western blot of lysates from HeLa cell line, mouse cerebellum tissue (from left to right) with Mouse Kdm6b Antibody. Antibody was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L (HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20 ug per lane.
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal (aa1023-1057) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
KDM6B / JMJD3 Antibody - Western blot analysis of extracts of various cell lines, using Kdm6b antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
KDM6B / JMJD3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KDM6B / JMJD3 Antibody - HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KDM6B / JMJD3 Rabbit anti-Human Polyclonal (aa1613-1662) Antibody
Human
WB
Unconjugated
100 µl/$397
Viewing 1-25 of 37 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).