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Anti-KDM2B / FBXL10 Antibody (aa1314-1326) IHC-plus™ LS-B2333

Note: This antibody replaces LS-C54822

Ordering

Wt. Vol. Conc. Price
50 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular KDM2B / FBXL10 Antibodies

Anti-KDM2B / FBXL10 Antibody (aa1314-1326) IHC-plus™ LS-B2333
Goat Polyclonal to Human KDM2B / FBXL10
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image
Anti-KDM2B / FBXL10 Antibody (C-Terminus) IHC-plus™ LS-B5649
Rabbit Polyclonal to Human KDM2B / FBXL10
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Chicken, Zebrafish
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-KDM2B / FBXL10 Antibody (C-Terminus, AP) LS-C278704
Rabbit Polyclonal (IgG) to Human KDM2B / FBXL10
Human
IHC, ELISA
AP Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human KDM2B / FBXL10
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken
IHC - Paraffin, ELISA
Unconjugated

Details

Human KDM2B / FBXL10
Goat
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Rabbit, Chicken (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (5 µg/ml)
  • ELISA (1:32000)

Specificity and Use

KDM2B / FBXL10 antibody was raised against synthetic peptide C-FGQVEEKLLQKLS from the C-terminus of human KDM2B / FBXL10 (NP_115979.3). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Dog, Bovine, Bat, Hamster, Elephant, Panda, Horse, Rabbit, Turkey, Chicken, Platypus (100%); Xenopus (85%).
LS-E25580 - Lyophilized - 100 µg - $145.00
aa1314-1326
Human KDM2B / FBXL10. This antibody is expected to recognize isoform a (NP_115979.3) only.
Immunohistochemistry: LS-B2333 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2333 was determined to be 5 ug/ml.

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About KDM2B / FBXL10

Q8NHM5 AL133572 CAB63721.2

KDM2B Antibody, CXXC2 Antibody, Fbl10 Antibody, F-box/LRR-repeat protein 10 Antibody, JHDM1B Antibody, F-box protein FBL10 Antibody, FBXL10 Antibody, Lysine-specific demethylase 2B Antibody, PCCX2 Antibody, Protein JEMMA Antibody

Histone demethylase that demethylates 'Lys-4' and 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' and dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation.

Immunohistochemistry

Immunohistochemistry
Anti-KDM2B antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2333 concentration 5 ug/ml.
 

Requested From: United States
Date Requested: 12/11/2016

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