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KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene Name: KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
Synonyms: KDELR2, ERD2-like protein 1, ERD2.2, ERD-2-like protein, KDEL receptor 2, ELP-1
Target Sequences: NM_006854 NP_006845.1 P33947

☰ Filters
Antibodies (24)
Proteins (7)
Over-Expression Lysate (6)
Primary (24)
Recombinant (1)
KDELR2 (31)
Human (24)
Mouse (7)
Rat (7)
Bovine (1)
Chicken (1)
Pig (1)
Sheep (1)
Zebrafish (1)
IHC (11)
IHC-P (4)
WB (24)
ELISA (8)
ICC (1)
IF (7)
Peptide-ELISA (2)
rabbit (24)
Product Group
IHCPlus (2)
IgG (15)
polyclonal pc (24)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (11)
aa183-211 (7)
C-Terminus (4)
50-130 aa, Internal (1)
Internal (1)
aa1-212 (1)
aa100-150 (1)
aa81-130 (1)
No (31)
GST (1)
Myc-DDK (Flag) (6)
Human (4)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
KDELR2 Antibody - Anti-KDELR2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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KDELR2 Rabbit anti-Human Polyclonal (aa100-150) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$440
KDELR2 Antibody - Immunohistochemical analysis of KDELR2 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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KDELR2 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Zebrafish, Pig, Mouse, Rat, Sheep, Bovine, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
KDELR2 Antibody - Anti-KDELR2 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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KDELR2 Rabbit anti-Human Polyclonal (aa81-130) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
KDELR2 Antibody - Western blot of KDEL Receptor 2 antibody
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KDELR2 Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
KDELR2 Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using ERD22 antibody.
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KDELR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
KDELR2 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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KDELR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KDELR2 Antibody - KDELR2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human cerebellum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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KDELR2 Rabbit anti-Human Polyclonal (aa183-211) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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KDELR2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
100 µl/$386
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KDELR2 Rabbit anti-Human Polyclonal (aa1-212) Antibody
Human
WB
Unconjugated
100 µg/$749
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KDELR2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$937
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KDELR2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$937
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KDELR2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$937
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KDELR2 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
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KDELR2 Rabbit anti-Human Polyclonal (PE) Antibody
Human
WB
PE Conjugated
100 µl/$937
KDELR2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
KDELR2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR2 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
KDELR2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
KDELR2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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KDELR2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
KDELR2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
21.1 kDa
100 µg/$494
Viewing 1-25 of 31 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).