KCNMB1

potassium large conductance calcium-activated channel, subfamily M, beta member 1

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate.

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Products

Antibodies (15)

Proteins (1)

Type

Primary (15)

Recombinant (1)

Target

KCNMB1 (16)

Reactivity

Human (15)

Mouse (3)

Rat (2)

Monkey (1)

Application

IHC (1)

WB (11)

ELISA (12)

IF (1)

Peptide-ELISA (1)

Host

rabbit (15)

Isotype

IgG (13)

Clonality

polyclonal pc (15)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (7)

Epitope

aa43-72 (7)

Publications

No (16)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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KCNMB1 Antibody LS-C807830

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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Human KCNMB1 Protein (Recombinant GST, N-terminus) (aa39-130) - LS-G59062

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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KCNMB1 Antibody LS-C767737

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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KCNMB1 Antibody (aa43-72) LS-C322402

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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KCNMB1 Antibody (aa43-72, Biotin) LS-C260951

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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KCNMB1 Antibody (aa43-72, FITC) LS-C260956

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

KCNMB1 Antibody (aa43-72, APC) LS-C260953

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

KCNMB1 Antibody (aa43-72, PE) LS-C260957

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

KCNMB1 Antibody (aa43-72, Azide-free, HRP) LS-C260958

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

KCNMB1 Antibody LS-C780165

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

KCNMB1 Antibody LS-C377528

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

KCNMB1 Antibody (HRP) LS-C377526

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

KCNMB1 Antibody (Biotin) LS-C377530

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

KCNMB1 Antibody (FITC) LS-C377529

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

KCNMB1 Antibody (aa43-72) LS-C165443

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal (aa43-72) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

KCNMB1 Antibody LS-C496931

Antibody:

KCNMB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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