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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNMA1 / BK Antibody (aa1098‑1196) LS‑C4182 Best Seller
BK antibody LS-C4182 is an unconjugated rabbit polyclonal antibody to BK (KCNMA1) from mouse and rat. Validated for IHC and WB.
Antibody
Catalog
Size
Price
LS-C4182-50
50 µl
$680

Popular KCNMA1 / BK Products

Anti-KCNMA1 antibody LS-A9574 IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin
Anti-KCNMA1 antibody LS-A9575 IHC of human breast, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bovine, Hamster, Horse, Pig, Rabbit, Chicken, Xenopus, Zebrafish
Applications: IHC, IHC - Paraffin
Anti-KCNMA1 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6604 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Guinea pig, Horse, Pig, Rabbit, Sheep, Chicken, Xenopus
Applications: IHC, IHC - Paraffin, Western blot
KCNMA1antibody IHC-paraffin: Rat Intestine Tissue.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot

Product Description

BK antibody LS-C4182 is an unconjugated rabbit polyclonal antibody to BK (KCNMA1) from mouse and rat. Validated for IHC and WB.
About KCNMA1 / BK
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. It is also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Q12791 NM_002247 NP_002238.2

KCNMA1 Antibody, BA205K10.1 Antibody, BKCA alpha subunit Antibody, BK channel Antibody, BKCA alpha Antibody, BKTM Antibody, HSlo Antibody, K(VCA)alpha Antibody, KCa1.1 Antibody, Maxi-K channel HSLO Antibody, MaxiK Antibody, KCNMA Antibody, SAKCA Antibody, SLO-ALPHA Antibody, Slowpoke homolog Antibody, Stretch-activated Kca channel Antibody, Slo homolog Antibody, BK channel alpha subunit Antibody, Maxi K channel Antibody, MSlo Antibody, MSLO1 Antibody, SLO Antibody, SLO1 Antibody


Specifications

Target
Mouse KCNMA1 / BK
Host
Rabbit
Reactivity
Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • Western blot (1:200 - 1:500)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
KCNMA1 / BK antibody was raised against gST fusion protein corresponding to residues 1098-1196 of mouse Slo (mSlo) (Accession A48206).
Epitope
aa1098-1196
Specificity
Recognizes BKCa Channel. Splice forms sequence homology: Corresponds to the C-terminus of the longer form of BKCa channel alpha subunit. Overlaps by >40 residues with a shorter form. Species cross-reactivity: Rat and mouse. Species sequence homology: Chicken: 91/99; rabbit: 88/99; turtle: 87/99.
Usage
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:200-1:500 (rat brain membranes). Preadsorption Control: 3 ug fusion protein (B2103A) per 1 ug antibody. Immunohistochemistry: Rat uterus and brain sections.
Presentation
PBS, pH 7.4, 1% BSA, 0.025% sodium azide, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 7/21/2018

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