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KCNK2 / TREK-1

potassium channel, subfamily K, member 2

TREK1 is a 2 pore-domain 4 transmembrane domain background potassium channel expressed throughout the central nervous system with lower levels in peripheral tissues. It is opened by polyunsaturated fatty acids, lysophospholipids, and volatile anesthetics. It is inhibited by neurotransmitters that increase intracellular cAMP or activate the Gq signaling pathway. Studies in mice suggest that TREK1 plays a role in neuroprotection against epilepsy and ischemia afforded by polyunsaturated fatty acids and lysophospholipids and in anesthesia induced by volatile anesthetics.

Gene Name: potassium channel, subfamily K, member 2
Family/Subfamily: Ion Channel , Potassium channel - two pore
Synonyms: KCNK2, HTREK-1c, K2p2.1, TREK-1 K(+) channel subunit, TREK1, Two-pore potassium channel 1, HTREK-1e, K2P2.1 potassium channel, TPKC1, TREK-1
Target Sequences: NM_001017424 NP_055032.1 O95069

☰ Filters
Antibodies (9)
Proteins (5)
Over-Expression Lysate (4)
Primary (9)
Recombinant (1)
KCNK2 / TREK-1 (14)
Human (8)
Mouse (4)
Rat (2)
Bovine (1)
WB (9)
ELISA (2)
Peptide-ELISA (1)
rabbit (9)
IgG (2)
polyclonal pc (9)
Biotin Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
Unconjugated (5)
N-Terminus (6)
aa1-100 (1)
aa4-14 (1)
No (14)
6His, N-terminus (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Yeast (1)
Purified (1)
Select
KCNK2 / TREK-1 Rabbit anti-Mouse Polyclonal (N-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
0.1 mg/$379
KCNK2 / TREK-1 Antibody - Detection of TREK 1 in human brain membrane lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (aa1-100) Antibody
Human
WB
Unconjugated
0.1 ml/$386
KCNK2 / TREK-1 Antibody - Detection of TREK 1 in human brain membrane lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Mouse, Bovine, Human
WB
Biotin Conjugated
0.1 ml/$416
KCNK2 / TREK-1 Antibody - Detection of TREK 1 in human brain membrane lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (N-Terminus) (DY650) Antibody
Human
WB
DY650 Conjugated
0.1 ml/$416
KCNK2 / TREK-1 Antibody - Detection of TREK 1 in human brain membrane lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (N-Terminus) (DY488) Antibody
Human
WB
DY488 Conjugated
0.1 ml/$416
KCNK2 / TREK-1 Antibody - Detection of TREK 1 in human brain membrane lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (N-Terminus) (DY550) Antibody
Human
WB
DY550 Conjugated
0.1 ml/$416
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (aa4-14) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$582
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
KCNK2 / TREK-1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$755
KCNK2 / TREK-1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
100 µg/$446; 20 µg/$336; 1 mg/$1,460
KCNK2 / TREK-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.7 kDa
20 µg/$215
KCNK2 / TREK-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
45.3 kDa
20 µg/$150
KCNK2 / TREK-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
45.3 kDa
100 µg/$494
KCNK2 / TREK-1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.7 kDa
100 µg/$710
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).