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KCNH2 / HERG
potassium voltage-gated channel, subfamily H (eag-related), member 2
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.
| Gene Name: | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
| Family/Subfamily: | Ion Channel , Potassium channel - Eag-related |
| Synonyms: | KCNH2, Eag homolog, HERG-1, ERG1, HERG, KV11.1, M-erg1, H-ERG, HERG1, SQT1, LQT2, Merg1, Eag-related protein 1, ERG-1 |
| Target Sequences: | NM_000238 NP_000229.1 Q12809 |
Publications (2)
1
Interaction with GM130 during HERG ion channel trafficking. Disruption by type 2 congenital long QT syndrome mutations. Human Ether--go-go-Related Gene. Roti EC, Myers CD, Ayers RA, Boatman DE, Delfosse SA, Chan EK, Ackerman MJ, January CT, Robertson GA. The Journal of biological chemistry. 2002 277:47779-85.
[PubMed:12270925]
2
Cardiac IKr channels minimally comprise hERG 1a and 1b subunits. Jones EM, Roti Roti EC, Wang J, Delfosse SA, Robertson GA. The Journal of biological chemistry. 2004 279:44690-4.
[PubMed:15304481]
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KCNH2 / HERG
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Fast Shipping
KCNH2 / HERG Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
KCNH2 / HERG Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
KCNH2 / HERG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
KCNH2 / HERG Rabbit anti-Mouse Polyclonal (aa895-944) Antibody
Mouse
WB
Unconjugated
100 µl/$424
KCNH2 / HERG Rabbit anti-Mouse Polyclonal (aa895-944) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
KCNH2 / HERG Rabbit anti-Mouse Polyclonal (aa895-944) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Rat, Human, Monkey
WB
FITC Conjugated
100 µl/$469
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
KCNH2 / HERG Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa886-899) Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KCNH2 / HERG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
KCNH2 / HERG Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
HRP Conjugated
100 µl/$1,063
KCNH2 / HERG Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
Biotin Conjugated
100 µl/$1,063
KCNH2 / HERG Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
FITC Conjugated
100 µl/$1,063
KCNH2 / HERG Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
APC Conjugated
100 µl/$1,063
KCNH2 / HERG Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
ELISA, ICC, IHC, IP, WB
PE Conjugated
100 µl/$1,063
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
KCNH2 / HERG Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
KCNH2 / HERG Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
200 µl/$952
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
KCNH2 / HERG Rabbit anti-Human Polyclonal (aa861-888) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
KCNH2 / HERG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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