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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNH2 / HERG Antibody (aa861‑888) LS‑C165420
HERG antibody LS-C165420 is an unconjugated rabbit polyclonal antibody to human HERG (KCNH2). Validated for Flow and WB.
Catalog
Size
Price
LS-C165420-400
400 µl
Unavailable

Popular KCNH2 / HERG Products

Anti-KCNH2 / Kv11.1 antibody LS-A9561 IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit
Applications: IHC, IHC - Paraffin
Immunohistochemistry Image
Species: Human, Mouse, Rat
Applications: IHC, Western blot, ELISA
KCNH2 / Kv11.1 antibody LS-C145542 Western blot of Mouse Kidney lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Dog, Guinea pig, Rabbit
Applications: Western blot
KCNH2 antibody Western blot. All lanes: Anti KCNH2 at 0.5 ug/ml. Lane 1: Rat Brain Tissue Lysate at 50 ug. Lane 2: HELA Whole Cell Lysate at 40 ug. Lane 3: COLO320 Whole Cell Lysate at 40 ug. Lane 4: MM231 Whole Cell Lysate at 40 ug. Predicted band size: 127 kD. Observed band size: 127 kD.
Species: Human, Rat
Applications: Western blot

Product Description

HERG antibody LS-C165420 is an unconjugated rabbit polyclonal antibody to human HERG (KCNH2). Validated for Flow and WB.
About KCNH2 / HERG
Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation. Q12809 NM_000238 NP_000229.1

KCNH2 Antibody, Eag homolog Antibody, HERG-1 Antibody, ERG1 Antibody, HERG Antibody, KV11.1 Antibody, M-erg1 Antibody, H-ERG Antibody, HERG1 Antibody, SQT1 Antibody, LQT2 Antibody, Merg1 Antibody, Eag-related protein 1 Antibody, ERG-1 Antibody


Specifications

Target
Human KCNH2 / HERG
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Flow Cytometry (1:10 - 1:50)
Blocking Peptide
LS-E9793 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C165420. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
aa861-888
Specificity
This KCNH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 861-888 amino acids from the Central region of human KCNH2.
Presentation
PBS, 0.09% sodium azide
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.
Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.

Flow Cytometry

KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.
Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.

Flow Cytometry

KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.
Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.

Flow Cytometry

KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Western blot

Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.
Western blot of KCNH2 Antibody in CEM cell line lysates (35 ug/lane). KCNH2 (arrow) was detected using the purified antibody.

Flow Cytometry

KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
KCNH2 Antibody flow cytometry of K562 cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.


Requested From: 
Date Requested: 6/17/2018

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