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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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KCNC1 / Kv3.1 Antibody (aa350‑400, DY488) LS‑C143299
Kv3.1 antibody LS-C143299 is a DY488-conjugated rabbit polyclonal antibody to Kv3.1 (KCNC1) from human, mouse, rat and other species. Validated for IP and WB.
Catalog
Size
Price
LS-C143299-100
100 µl
Unavailable

Popular KCNC1 / Kv3.1 Products

Antibody
Species: Human, Mouse, Rat
Applications: IHC, ICC, Immunofluorescence, Western blot
Antibody
Species: Human
Applications: IHC, Western blot, ELISA
KV3.1 (S16B-8), Mouse brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
KV3.1 (S16B-8), Mouse brain.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Rat, Human, Mouse
Applications: IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Human, Mouse, Rat, Bovine, Rabbit
Applications: IHC, IHC - Paraffin, Western blot

Product Description

Kv3.1 antibody LS-C143299 is a DY488-conjugated rabbit polyclonal antibody to Kv3.1 (KCNC1) from human, mouse, rat and other species. Validated for IP and WB.
About KCNC1 / Kv3.1
Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. P48547 NM_004976 NP_004967.1

KCNC1 Antibody, KShIIIB Antibody, KV3.1 Antibody, Raw2 Antibody, Shaw22 Antibody, KV4 Antibody, NGK2 Antibody


Specifications

Target
Rat KCNC1 / Kv3.1
Host
Rabbit
Reactivity
Rat, Human, Mouse, Bovine, Dog, Rabbit (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
DyLight 488. Also available Unconjugated or conjugated with Biotin, DY650, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Immunoprecipitation (1:500 - 1:1000)
  • (applications tested for the base form of this product only)
Immunogen
KCNC1 / Kv3.1 antibody was raised against synthetic peptide made to an internal portion of rat Kv3.1 (within residues 350-400). [Swiss-Prot# P25122]
Epitope
aa350-400
Specificity
Does not cross-react with Kv1.2 or Kv1.3.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
50 mM sodium borate
Storage
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen.. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen..  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Kv3.1 Antibody - Membrane preparations from HEK-293 cells untransfected (lane 1), transfected with Kv3.1 (lanes 2 and 4) and transfected with Kv1.2 (lane 3) were subjected to SDS-PAGE and were Western blotted with Kv3.1 Antibody. Lane 4 was probed with antibody that had been preincubated with the peptide used as immunogen.. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/25/2018

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