Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
This HWA4C4 antibody has been tested by immunoblot of lysine-63-linked polyubiquitin chains. This can be used at less than or equal to 2 ug/ml. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Western Blot of polyubiquitin chains with anti-Ub-K63 mouse monoclonal antibody. In vitro linked, then purified polyubiquitin chains were analyzed by SDS-PAGE followed by immunoblotting with anti-Ub-K63 (HWA4C4). The antibody detects lysine-63-linked chains (lane 1), but does not detect lysine-48-linked chains (lane 2).