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JUP/CTNNG/Junction Plakoglobin

junction plakoglobin

Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton.

Gene Name: junction plakoglobin
Family/Subfamily: Catenin , not assigned-Catenin
Synonyms: JUP, Desmoplakin-3, CTNNG, DPIII, Gamma catenin, Junction plakoglobin, PKGB, ARVD12, Catenin gamma, Desmoplakin III, DP3, PDGB
Target Sequences: NM_002230 NP_002221.1 P14923

Publications (1)

1
Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. Cooksley-Decasper S, Reiser H, Thommen DS, Biedermann B, Neidhart M, Gawinecka J, Cathomas G, Franzeck FC, Wyss C, Klingenberg R, Nanni P, Roschitzki B, Matter C, Wolint P, Emmert MY, Husmann M, Amann-Vesti B, Maier W, Gay S, Lüscher TF, von Eckardstein A. PloS one. 2012 7:e47985. (WB; Human) [Full Text Article] [PubMed:23110151] [PMC:PMC3480477] Related Antibodies: LS-B4364, LS-B6046, LS-B5502, LS-C21269.

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Antibodies (79)
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JUP/CTNNG/Junction Plakoglobin (93)
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JUP/CTNNG/Junction Plakoglobin Antibody - Anti-Gamma Catenin antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (2G9) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$460
JUP/CTNNG/Junction Plakoglobin Antibody - Anti-Gamma Catenin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (aa696-745) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
JUP/CTNNG/Junction Plakoglobin Antibody - Anti-Gamma Catenin antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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JUP/CTNNG/Junction Plakoglobin Goat anti-Human Polyclonal (aa732-745) Antibody
Rabbit, Mouse, Dog, Hamster, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
JUP/CTNNG/Junction Plakoglobin Antibody - Anti-Gamma Catenin antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P
Unconjugated
250 µl/$460
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (aa45-114) Antibody
Human
IF, IP, WB
Unconjugated
100 µg/$801
JUP/CTNNG/Junction Plakoglobin Antibody - Immunohistochemical analysis of Gamma-catenin staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rabbit, Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
JUP/CTNNG/Junction Plakoglobin Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with JUP Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (aa636-663) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
JUP/CTNNG/Junction Plakoglobin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (aa636-663) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
JUP/CTNNG/Junction Plakoglobin Antibody - Immunofluorescence analysis of HeLa cells.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Bovine Monoclonal (PG 5.1) Antibody
Chicken, Bovine, Mouse, Rat, Human
ICC, IHC, IP, WB
Unconjugated
50 µg/$891
JUP/CTNNG/Junction Plakoglobin Antibody - Anti-JUP/CTNNG/Junction Plakoglobin antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
JUP/CTNNG/Junction Plakoglobin Antibody - gamma Catenin Antibody in Immunohistochemistry (IHC)
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (4C12) Antibody
Human
ICC, IF, IHC, WB
Unconjugated
100 µl/$518
JUP/CTNNG/Junction Plakoglobin Antibody - IHC of paraffin-embedded rectum tissues using JUP mouse monoclonal antibody with DAB staining.
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (4C12) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µl/$459
JUP/CTNNG/Junction Plakoglobin Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded rectum tissues with DAB staining using Catenin-gamma Monoclonal Antibody.
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JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
JUP/CTNNG/Junction Plakoglobin Antibody - Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (aa695-745) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
JUP/CTNNG/Junction Plakoglobin Antibody - Catenin-gamma antibody for IHC in human colon tissue.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
JUP/CTNNG/Junction Plakoglobin Mouse anti-Chicken Monoclonal Antibody
Chicken, Rat, Human
ICC, IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$564
JUP/CTNNG/Junction Plakoglobin Antibody - 1:200 staining human kidney tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
JUP/CTNNG/Junction Plakoglobin Antibody - gamma Catenin antibody IHC-paraffin: Human Intestinal Cancer Tissue.
Select
JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (aa556-745) Antibody
Mouse, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
JUP/CTNNG/Junction Plakoglobin Antibody - Western blot of Catenin-gamma antibody
Select
JUP/CTNNG/Junction Plakoglobin Rabbit anti-Human Polyclonal (670-750 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal Antibody
Human
ICC, IHC, IP, WB
Unconjugated
100 µg/$832
JUP/CTNNG/Junction Plakoglobin Antibody - IHC testing of FFPE human cervical carcinoma with Gamma Catenin antibody (clone CTNG/1483). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
Select
JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (CTNG/1664) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
JUP/CTNNG/Junction Plakoglobin Antibody - IHC testing of FFPE human cervical carcinoma with Gamma Catenin antibody (clone CTNG/1483). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
Select
JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (CTNG/1664) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
JUP/CTNNG/Junction Plakoglobin Antibody - IHC testing of FFPE human cervical carcinoma with Plakoglobin antibody (clone CTNG/1483). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9, for 10-20 min.
Select
JUP/CTNNG/Junction Plakoglobin Mouse anti-Human Monoclonal (CTNG/1483) Antibody
Human
Flo, IF, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
Viewing 1-25 of 93 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).