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JMJD7 encodes a highly conserved protein with a JmjC domain, which are part of the cupin metalloenzyme superfamily. JmjC proteins may function as 2-oxoglutarate-Fe(II)-dependent dioxygenases. Most tissues also express read-through transcripts from this gene into the downstream phospholipase A2, group IVB (cytosolic) gene, some of which may encode fusion proteins combining the N-terminus of this protein with the phospholipase A2, group IVB protein.
Gene Name: | jumonji domain containing 7 |
Family/Subfamily: | Phospholipase , not assigned-Phospholipase |
Synonyms: | JMJD7, CPLA2-BETA, Jumonji domain containing 7 |
Target Sequences: | NM_005090 NP_005081.1 P0C870 |
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