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Anti-JAG1 / Jagged 1 Antibody (aa110-125) IHC-plus™ LS-B2442

Note: This antibody replaces LS-C24920


Wt. Vol. Conc. Price
50 µg - 1 mg/ml $395

LSBio (Direct) LSBio (Direct)

JAG1 / Jagged 1 Antibody LS-B2442 Images

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Anti-JAG1 / Jagged 1 antibody IHC of human kidney.

100% Guaranteed 100% Guaranteed Publications Publications (4)
Rabbit Polyclonal (IgG) to Human JAG1 / Jagged 1
IHC - Paraffin, ICC, Immunofluorescence, Western blot, ELISA


Human JAG1 / Jagged 1
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Protein A purified


IHC - Paraffin (5 µg/ml), ICC, Immunofluorescence (1:100 - 1:500), Western blot (1:250 - 1:1000), ELISA (1:2500 - 1:10000)

Specificity and Use

JAG1 / Jagged 1 antibody was raised against synthetic peptide corresponding to aa 110-125 of human Jagged-1protein.
Recognizes human Jagged1 (JAG1).
Immunohistochemistry: LS-B2442 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2442 was determined to be 5 ug/ml.


PBS, pH 7.2, 0.01% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

Publications (4)

Differential expression of Notch receptors and their ligands in desmoplastic ameloblastoma. Siar CH, Nakano K, Han PP, Nagatsuka H, Ng KH, Kawakami T. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2010 39:552-8. (IHC-P; Human) [PubMed:20337864]
Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype. Siar CH, Nagatsuka H, Chuah KS, Rivera RS, Nakano K, Ng KH, Kawakami T. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 110:224-33. (IHC-P; Human) [PubMed:20659700]
Immunolocalization of notch signaling protein molecules in a maxillary chondrosarcoma and its recurrent tumor. Siar CH, Ha KO, Aung LO, Nakano K, Tsujigiwa H, Nagatsuka H, Ng KH, Kawakami T. European journal of medical research. 2010 15:456-60. (IHC-P; Human) [Full Text Article] [PubMed:21156405] [PMC:PMC3352190]
Notch signaling and ghost cell fate in the calcifying cystic odontogenic tumor. Siar CH, Kawakami T, Buery RR, Nakano K, Tomida M, Tsujigiwa H, Han PP, Nagatsuka H, Ng KH. European journal of medical research. 2011 16:501-6. (IHC-P; Human) [PubMed:22027644] [PMC:PMC3351808]

About JAG1 / Jagged 1

P78504 NM_000214 NP_000205.1

JAG1 Antibody, AGS Antibody, AHD Antibody, Alagille syndrome Antibody, CD339 antigen Antibody, HJ1 Antibody, Jagged1 Antibody, JAGL1 Antibody, Jagged Antibody, Jagged 1 Antibody, Protein jagged-1 Antibody, AWS Antibody, CD339 Antibody, Soluble protein jagged Antibody

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).


Anti-JAG1 / Jagged 1 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2442 concentration 5 ug/ml.

Requested From: United States
Date Requested: 10/6/2015

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