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IWS1

IWS1 homolog (S. cerevisiae)

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Gene Name: IWS1 homolog (S. cerevisiae)
Synonyms: IWS1, IWS1L, Protein IWS1 homolog, Interacts with Spt6, IWS1 homolog (S. cerevisiae), IWS1-like protein
Target Sequences: G26921

☰ Filters
Antibodies (13)
Primary (13)
IWS1 (13)
Human (13)
Mouse (4)
Rat (3)
Chimpanzee (3)
Gibbon (3)
Orangutan (3)
IHC (4)
IHC-P (2)
WB (11)
ELISA (4)
IF (3)
IP (3)
Peptide-ELISA (1)
rabbit (13)
IgG (8)
polyclonal pc (13)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
aa71-120 (4)
N-Terminus (1)
aa1-50 (1)
aa591-743 (1)
No (13)
IWS1 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer at dilution 1:100
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
IWS1 Antibody - Immunofluorescence analysis of A549 cells.
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
IWS1 Antibody
Select
IWS1 Rabbit anti-Human Polyclonal (aa591-743) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
Select
IWS1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IF, IP, WB
Unconjugated
100 µl/$688
IWS1 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
IWS1 Antibody - Detection of human and mouse IWS1 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-IWS1 antibody used for WB at 0.4 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Select
IWS1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
IWS1 Antibody - Western blot analysis of extracts of HeLa cells using IWS1 antibody. The lane on the left was treated with blocking peptide.
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IWS1 Antibody - Immunofluorescence analysis of A549 cells using IWS1 Polyclonal Antibody.
Select
IWS1 Rabbit anti-Human Polyclonal Antibody
Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
IWS1 Antibody - IWS1 antibody Western Blot of Human Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IWS1 Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
IWS1 Antibody - IWS1 antibody Western Blot of Human Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IWS1 Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Human, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
IWS1 Antibody - IWS1 antibody Western Blot of Human Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IWS1 Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Human, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
IWS1 Antibody - IWS1 antibody Western Blot of Human Kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
IWS1 Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Human, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
Viewing 1-13 of 13 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).