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Anti-IVL / Involucrin Antibody (clone SY5) LS-C357940

Catalog Size Price
LS-C357940-20 20 µg Unavailable
LS-C357940-100 100 µg Unavailable

Most Popular IVL / Involucrin Antibodies

Anti-IVL / Involucrin Antibody (aa420-578) IHC-plus™ LS-B3058
Rabbit Polyclonal to Human IVL / Involucrin
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IVL / Involucrin Antibody (clone SY5) IHC-plus™ LS-B6298
Mouse Monoclonal [clone SY5] (IgG1) to Human IVL / Involucrin
Human, Monkey, Dog, Pig
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IVL / Involucrin Antibody (clone IL-9) LS-C171169
Mouse Monoclonal [clone IL-9] (IgG1) to Human IVL / Involucrin
Human, Dog, Pig
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Unconjugated
Anti-IVL / Involucrin Antibody (aa301-460) LS-C294948
Rabbit Polyclonal (IgG) to Mouse IVL / Involucrin
Mouse
Western blot, ELISA
Unconjugated
Western blot Image
Anti-IVL / Involucrin Antibody (clone SY5) LS-C357940
Mouse Monoclonal [clone SY5] (IgG1,k) to Human IVL / Involucrin
Human, Gorilla, Dog, Pig, Owl monkey
IHC - Paraffin, Immunofluorescence, Flow Cytometry
Unconjugated

100% Guaranteed
Mouse Monoclonal [clone SY5] (IgG1,k) to Human IVL / Involucrin
Human, Gorilla, Dog, Pig, Owl monkey
IHC - Paraffin, Immunofluorescence, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Human IVL / Involucrin
Mouse
Human, Gorilla, Dog, Pig, Owl monkey (tested or 100% immunogen sequence identity)
Mouse
IgG1,k Monoclonal [SY5]
Unconjugated
Protein G purified
Unmodified. Also available Azide-free, Ready-to-Use.

Applications

  • IHC - Paraffin (1 - 2 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
  • Flow Cytometry (0.5 - 1 µg/10E6 cells)
  • (applications tested for the base form of this product only)

Specificity and Use

Purified Involucrin from human keratinocytes.
Human IVL / Involucrin
This antibody recognizes a protein of 66-170kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this antibody reacts with a 120kDa protein. It stains the involucrin in a variety of sizes: 170kDa in MCF-7 cells, a doublet of ~115 and 150kDa in gorilla and owl monkey, 66kDa in dog, and a doublet of 105kDa in pig. Its epitope maps between amino acids 421-568 of human involucrin. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal. expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.

Packaging

PBS, pH 7.4, 0.1 mg/ml BSA, 0.05% sodium azide
2°C to 8°C
For research use only.

About IVL / Involucrin

P07476 NM_005547 NP_005538.2

IVL Antibody, Involucrin Antibody

Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.

Requested From: 
Date Requested: 11/18/2017

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