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Anti-IVL / Involucrin Antibody (clone INVO49, Azide-free) LS-C391926

Catalog Size Price
LS-C391926-100 100 µg (1 mg/ml) Unavailable

Most Popular IVL / Involucrin Antibodies

Anti-IVL / Involucrin Antibody (aa420-578) IHC-plus™ LS-B3058
Rabbit Polyclonal to Human IVL / Involucrin
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-IVL / Involucrin Antibody (clone SY5) IHC-plus™ LS-B6298
Mouse Monoclonal [clone SY5] (IgG1) to Human IVL / Involucrin
Human, Monkey, Dog, Pig
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-IVL / Involucrin Antibody (clone IL-9) LS-C171169
Mouse Monoclonal [clone IL-9] (IgG1) to Human IVL / Involucrin
Human, Dog, Pig
IHC - Paraffin, IHC - Frozen, ICC, Western blot
Unconjugated
Anti-IVL / Involucrin Antibody (aa301-460) LS-C294948
Rabbit Polyclonal (IgG) to Mouse IVL / Involucrin
Mouse
Western blot, ELISA
Unconjugated
Western blot Image
Anti-IVL / Involucrin Antibody (clone SY5) LS-C357940
Mouse Monoclonal [clone SY5] (IgG1,k) to Human IVL / Involucrin
Human, Gorilla, Dog, Pig, Owl monkey
IHC - Paraffin, Immunofluorescence, Flow Cytometry
Unconjugated

100% Guaranteed
Mouse Monoclonal [clone INVO49] (IgG1,k) to Human IVL / Involucrin
Human
IHC - Paraffin, Immunofluorescence (applications tested for the base form of this product only)
Unconjugated, Azide-free

Details

Human IVL / Involucrin
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [INVO49]
Unconjugated
Protein G purified
Azide-free. Also available Unmodified or Ready-to-Use.

Applications

  • IHC - Paraffin (0.1 - 0.2 µg/ml)
  • Immunofluorescence (1 - 2 µg/ml)
  • (applications tested for the base form of this product only)

Specificity and Use

Purified protein.
Human IVL / Involucrin
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. Titering of the Involucrin antibody may be required for optimal performance. Staining of formalin-fixed tissues is enhanced by digestion with Trypsin or Protease XXV at 1mg/ml PBS for 5 min at 37oC. Enzyme digestion is more effective than Citrate buffer based epitope unmasking.

Packaging

Sterile PBS.
2°C to 8°C
For research use only.

About IVL / Involucrin

P07476 NM_005547 NP_005538.2

IVL Antibody, Involucrin Antibody

Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.

Immunohistochemistry

Immunohistochemistry
IHC testing of FFPE human tonsil with Involucrin antibody (clone INVO49). This image was taken for the unmodified form of this product. Other forms have not been tested.

Requested From: 
Date Requested: 11/18/2017

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