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IVL / Involucrin Antibody (clone INVO49, Azide‑free) LS‑C391926
Involucrin antibody LS-C391926 is an unconjugated mouse monoclonal antibody to human Involucrin (IVL). Validated for IF and IHC.
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Review This ProductPopular IVL / Involucrin Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Dog, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, ELISA
Species:
Human, Dog, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Species:
Human, Gorilla, Dog, Pig, Owl monkey
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Flow Cytometry
Product Description
Involucrin antibody LS-C391926 is an unconjugated mouse monoclonal antibody to human Involucrin (IVL). Validated for IF and IHC.
About IVL / Involucrin
Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
P07476
NM_005547
NP_005538.2
IVL Antibody, Involucrin Antibody
Specifications
Target
Human IVL / Involucrin
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
[INVO49]
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free.
Also available Unmodified or Ready-to-Use.
Applications
- IHC
- IHC - Paraffin (0.1 - 0.2 µg/ml)
- Immunofluorescence (1 - 2 µg/ml)
- (applications tested for the base form of this product only)
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Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
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Immunogen
Purified protein.
Specificity
Human IVL / Involucrin
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. Titering of the Involucrin antibody may be required for optimal performance. Staining of formalin-fixed tissues is enhanced by digestion with Trypsin or Protease XXV at 1mg/ml PBS for 5 min at 37oC. Enzyme digestion is more effective than Citrate buffer based epitope unmasking.
Presentation
Sterile PBS.
Storage
Store at 2°C to 8°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Customer Reviews (0)
Images
Immunohistochemistry
IHC testing of FFPE human tonsil with Involucrin antibody (clone INVO49). This image was taken for the unmodified form of this product. Other forms have not been tested.
Immunohistochemistry
IHC testing of FFPE human tonsil with Involucrin antibody (clone INVO49). This image was taken for the unmodified form of this product. Other forms have not been tested.
Immunohistochemistry
IHC testing of FFPE human tonsil with Involucrin antibody (clone INVO49). This image was taken for the unmodified form of this product. Other forms have not been tested.
Immunohistochemistry
IHC testing of FFPE human tonsil with Involucrin antibody (clone INVO49). This image was taken for the unmodified form of this product. Other forms have not been tested.
Requested From:
Date Requested: 7/20/2018
Date Requested: 7/20/2018
