Human IVL / Involucrin

Mouse

Human (tested or 100% immunogen sequence identity)

IgG1,k Monoclonal

INVO49

Unconjugated

Protein G purified

Azide-free, BSA-free. Also available Unmodified or Ready-to-Use.

Purified protein

Human IVL / Involucrin

• IHC
• IHC - Paraffin (0.1 - 0.2 µg/ml)
• Immunofluorescence (1 - 2 µg/ml)

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Involucrin is a highly reactive, soluble, transglutaminase substrate protein present in keratinocytes of epidermis and other stratified squamous epithelia. It first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase thus helping in the formation of an insoluble envelope beneath the plasma membrane functioning as a glutamyl donor during assembly of the cornified envelope. Titering of the Involucrin antibody may be required for optimal performance. Staining of formalin-fixed tissues is enhanced by digestion with Trypsin or Protease XXV at 1mg/ml PBS for 5 min at 37oC. Enzyme digestion is more effective than Citrate buffer based epitope unmasking.

1X PBS

Store at 2°C to 8°C.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P07476 NCBI: NM_005547 NP_005538.2