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ITPR1 / IP3 Receptor Type 1
inositol 1,4,5-trisphosphate receptor, type 1
This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.
| Gene Name: | inositol 1,4,5-trisphosphate receptor, type 1 |
| Family/Subfamily: | Ion Channel , Inositol 1,4,5-triphosphate receptor |
| Synonyms: | ITPR1, InsP3R-I, IP3R1, InsP3R, InsP3R type I, INSP3R1, IP3R, Opisthotonus, Pcp1, IP3 receptor, IP3 receptor isoform 1, SCA15, Spinocerebellar ataxia 15, Spinocerebellar ataxia 16, I145TR, IP3R 1, KIAA1754, SCA16, Type 1 InsP3 receptor |
| Target Sequences: | NM_001099952 NP_002213.5 Q14643 |
Publications (4)
1
The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X. Nature communications. 2017 8:15279. (WB; Human)
[Full Text Article]
[PubMed:28589943]
[PMC:PMC5467231]
2
PC-PLC is involved in osteoclastogenesis induced by TNF- alpha through upregulating IP3R1 expression. Xia L, Zhang D, Wang C, Wei F, Hu Y. FEBS letters. 2012 Sep;586:3341-8. [Full Text Article]
[PubMed:22819818]
Related Antibodies: LS-B2640.
3
Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10. Finton KA, Larimore K, Larman HB, Friend D, Correnti C, Rupert PB, Elledge SJ, Greenberg PD, Strong RK. PLoS pathogens. 2013 9:e1003639. [Full Text Article]
[PubMed:24086134]
[PMC:PMC3784475]
Related Antibodies: LS-B2627.
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(29)
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(3)
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ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa1892-1911) Antibody
Mouse, Bovine, Rat, Human, Monkey
ICC, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$485
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$485
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Rat Polyclonal (pSer1756) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$689
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (1540-1620 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa1566-1615) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa1025-1050) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa2708-2758) Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa2411-2758) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (1540-1620 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (pSer1598/1588) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (1700-1780 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (aa700-750) Antibody
Human
IHC
Unconjugated
100 µl/$393
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (pSer1764) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
ITPR1 / IP3 Receptor Type 1 Rabbit-New Zealand White anti-Human Polyclonal (aa1140-1190) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal (pSer1756) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ITPR1 / IP3 Receptor Type 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
ITPR1 / IP3 Receptor Type 1 Mouse anti-Human Monoclonal (2B6) Antibody
Human
ELISA
Unconjugated
100 µg/$423
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product results
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